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Volume 10, Issue 5

Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 10, Issue 5 (2014)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 10, Issue 5 (2014)

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Editorial

The successes and failures of physiologically based pharmacokinetic modeling: there is room for improvement

Italo Poggesi ChemD, Jan Snoeys PhD & Achiel Van Peer PhD

Pages: 631-635

Published online: 11 Feb 2014

AbstractforThe successes and failures of physiologically based pharmacokinetic modeling: there is room for improvement | Full Text | References | PDF (348.3 KB)

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Reviews

Review Article

The impact of DNA methylation technologies on drug toxicology

Alfonso Dueñas-Gonzalez, Brenda Alatorre & Aurora Gonzalez-Fierro

Pages: 637-646

Published online: 25 Mar 2014

AbstractforThe impact of DNA methylation technologies on drug toxicology | Full Text | References | PDF (288.2 KB)

289 Views
8 CrossRef citations
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Review Article

Evaluating SGLT2 inhibitors for type 2 diabetes: pharmacokinetic and toxicological considerations

André J Scheen

Pages: 647-663

Published online: 03 Jan 2014

AbstractforEvaluating SGLT2 inhibitors for type 2 diabetes: pharmacokinetic and toxicological considerations | Full Text | References | PDF (424.8 KB)

2158 Views
49 CrossRef citations
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Review Article

Data mining for potential adverse drug–drug interactions

Felix Hammann MD PhD & Juergen Drewe (Professor) MD MSc

Pages: 665-671

Published online: 04 Mar 2014

AbstractforData mining for potential adverse drug–drug interactions | Full Text | References | PDF (196.5 KB)

529 Views
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Review Article

Pharmacokinetic considerations for therapies used to treat interstitial cystitis

Barbara Gardella MD, Daniele Porru MD, Massimo Allegri MD, Stefano Bogliolo MD, Anna Daniela Iacobone MD, Cristina Minella MD, Rossella Elena Nappi MD PhD, Simone Ferrero MD PhD & Arsenio Spinillo MD PhD

Pages: 673-684

Published online: 12 Mar 2014

AbstractforPharmacokinetic considerations for therapies used to treat interstitial cystitis | Full Text | References | PDF (389.2 KB)

256 Views
5 CrossRef citations
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Review Article

In vivo zebrafish assays for analyzing drug toxicity

Demetrio Raldúa & Benjamin Piña

Pages: 685-697

Published online: 11 Mar 2014

AbstractforIn vivo zebrafish assays for analyzing drug toxicity | Full Text | References | PDF (565 KB)

835 Views
67 CrossRef citations
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Review Article

Pharmacogenetic considerations for acute lymphoblastic leukemia therapies

Stéphanie Dulucq, Caroline Laverdière, Daniel Sinnett & Maja Krajinovic

Pages: 699-719

Published online: 27 Mar 2014

AbstractforPharmacogenetic considerations for acute lymphoblastic leukemia therapies | Full Text | References | PDF (483.3 KB)

409 Views
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Review Article

Clinically relevant interactions between newer antidepressants and second-generation antipsychotics

Edoardo Spina (Professor) & Jose de Leon

Pages: 721-746

Published online: 05 Feb 2014

AbstractforClinically relevant interactions between newer antidepressants and second-generation antipsychotics | Full Text | References | PDF (683.8 KB)

2239 Views
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Drug Evaluations

Febuxostat: drug review and update

Harmanjot K Grewal (Assistant Professor of Clinical Medicine) MD, Joseph R Martinez (First Year Fellow) MD & Luis R Espinoza (Chief, Professor of Medicine) MD

Pages: 747-758

Published online: 01 Apr 2014

Abstractfor Febuxostat: drug review and update | Full Text | References | PDF (433.9 KB)

879 Views
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Pharmacokinetic evaluation of vortioxetine for the treatment of major depressive disorder

Steven L Dubovsky MD

Pages: 759-766

Published online: 01 Apr 2014

AbstractforPharmacokinetic evaluation of vortioxetine for the treatment of major depressive disorder | Full Text | References | PDF (293.2 KB)

586 Views
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Research Article

Article

Pages: i-ii

Published online: 09 Apr 2014

48 Views
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