Expert Opinion on Drug Metabolism & Toxicology, Volume 11, Issue 2 (2015)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 11, Issue 2 (2015)

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Editorial

Editorial
The therapeutic armamentarium in migraine is quite elderly
Paolo Martelletti
Pages: 175-177
Published online: 01 Dec 2014
AbstractforThe therapeutic armamentarium in migraine is quite elderly | Full Text | References | PDF (128.4 KB)
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Free Access

Original Research

Article
Ethnic sensitivity assessment – pharmacokinetic comparability between Japanese and non-Japanese healthy subjects on selected mAbs
Soichiro Matsushima PhD, Yue Huang PhD, Hikoe Suzuki, Junichi Nishino & Peter Lloyd PhD
Pages: 179-191
Published online: 18 Dec 2014
AbstractforEthnic sensitivity assessment – pharmacokinetic comparability between Japanese and non-Japanese healthy subjects on selected mAbs | Full Text | References | PDF (353.6 KB)
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Review

Review Article
Abuse-deterrent formulations: part 1 – development of a formulation-based classification system
David J Mastropietro & Hossein Omidian PhD
Pages: 193-204
Published online: 06 Nov 2014
AbstractforAbuse-deterrent formulations: part 1 – development of a formulation-based classification system | Full Text | References | PDF (310 KB)
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Clinical pharmacokinetics and pharmacodynamics of ganciclovir and valganciclovir in children with cytomegalovirus infection
Chris Stockmann, Jessica K Roberts, Elizabeth D Knackstedt, Michael G Spigarelli & Catherine MT Sherwin
Pages: 205-219
Published online: 27 Nov 2014
AbstractforClinical pharmacokinetics and pharmacodynamics of ganciclovir and valganciclovir in children with cytomegalovirus infection | Full Text | References | PDF (554.1 KB)
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Animal models for exploring the pharmacokinetics of breast cancer therapies
Omar M Rashid MD JD & Kazuaki Takabe MD PhD FACS
Pages: 221-230
Published online: 21 Nov 2014
AbstractforAnimal models for exploring the pharmacokinetics of breast cancer therapies | Full Text | References | PDF (257.7 KB)
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Formation of reactive metabolites and management of tyrosine kinase inhibitor-induced hepatotoxicity: a literature review
Yi Ling Teo, Han Kiat Ho & Alexandre Chan
Pages: 231-242
Published online: 15 Nov 2014
AbstractforFormation of reactive metabolites and management of tyrosine kinase inhibitor-induced hepatotoxicity: a literature review | Full Text | References | PDF (762.4 KB)
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Current understanding of the mechanisms of idiosyncratic drug-induced agranulocytosis
Alexander Johnston & Jack Uetrecht
Pages: 243-257
Published online: 26 Nov 2014
AbstractforCurrent understanding of the mechanisms of idiosyncratic drug-induced agranulocytosis | Full Text | References | PDF (587.8 KB)
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Applying machine learning techniques for ADME-Tox prediction: a review
Vinícius Gonçalves Maltarollo, Jadson Castro Gertrudes, Patrícia Rufino Oliveira & Kathia Maria Honorio
Pages: 259-271
Published online: 02 Dec 2014
AbstractforApplying machine learning techniques for ADME-Tox prediction: a review | Full Text | References | PDF (489.5 KB)
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New insights in the biology of ABC transporters ABCC2 and ABCC3: impact on drug disposition
Lori WE van der Schoor, Henkjan J Verkade, Folkert Kuipers & Johan W Jonker
Pages: 273-293
Published online: 07 Nov 2014
AbstractforNew insights in the biology of ABC transporters ABCC2 and ABCC3: impact on drug disposition | Full Text | References | PDF (593.3 KB)
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Drug Evaluation

Pharmacology and clinical efficacy of dalfampridine for treating multiple sclerosis
Alessandra Lugaresi MD PhD
Pages: 295-306
Published online: 16 Dec 2014
AbstractforPharmacology and clinical efficacy of dalfampridine for treating multiple sclerosis | Full Text | References | PDF (502.7 KB)
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Tocilizumab for treating rheumatoid arthritis: an evaluation of pharmacokinetics/pharmacodynamics and clinical efficacy
Soken-Nakazawa J Song MD PhD & Kazuyuki Yoshizaki (Professor) MD PhD
Pages: 307-316
Published online: 10 Dec 2014
AbstractforTocilizumab for treating rheumatoid arthritis: an evaluation of pharmacokinetics/pharmacodynamics and clinical efficacy | Full Text | References | PDF (266.8 KB)
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Evaluation of pharmacokinetics and pharmacodynamics and clinical efficacy of certolizumab pegol for Crohn’s disease
Gloria SZ Tun & Alan J Lobo (Professor)
Pages: 317-327
Published online: 14 Jan 2015
AbstractforEvaluation of pharmacokinetics and pharmacodynamics and clinical efficacy of certolizumab pegol for Crohn’s disease | Full Text | References | PDF (547.6 KB)
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Further Readings

Related articles
Page: 1
Published online: 14 Jan 2015
CitationforRelated articles | Full Text | PDF (85.8 KB)
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