Expert Opinion on Drug Metabolism & Toxicology, Volume 13, Issue 7 (2017)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 13, Issue 7 (2017)

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Editorial

Editorial
Prediction and management of drug reaction with eosinophilia and systemic symptoms (DRESS)
Tetsuo Shiohara, Yoko Kano, Kazuhisa Hirahara & Yumi Aoyama
Pages: 701-704
Published online: 01 Mar 2017
First Page PreviewforPrediction and management of drug reaction with eosinophilia and systemic symptoms (DRESS) | Full Text | References | PDF (465.3 KB)
  • 6998 Views
  • 24 CrossRef citations
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Free Access

Review

Review
Predicting and preventing antimicrobial resistance utilizing pharmacodynamics: part II Gram-negative bacteria
Kamilia Abdelraouf, Kristin E. Linder, Michael D. Nailor & David P. Nicolau
Pages: 705-714
Published online: 19 May 2017
AbstractforPredicting and preventing antimicrobial resistance utilizing pharmacodynamics: part II Gram-negative bacteria | Full Text | References | PDF (784.2 KB)
  • 339 Views
  • 8 CrossRef citations
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Review
Pharmacokinetics, pharmacodynamics and pharmacogenetics associated with nonsteroidal anti-inflammatory drugs and opioids in pediatric cancer patients
Jonathan E. Constance, Sarah C. Campbell, Amit A. Somani, Venkata Yellepeddi, Katie H. Owens & Catherine M. T. Sherwin
Pages: 715-724
Published online: 05 Jun 2017
AbstractforPharmacokinetics, pharmacodynamics and pharmacogenetics associated with nonsteroidal anti-inflammatory drugs and opioids in pediatric cancer patients | Full Text | References | PDF (781.3 KB)
  • 477 Views
  • 13 CrossRef citations
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Review
The genetic basis of antiplatelet and anticoagulant therapy: A pharmacogenetic review of newer antiplatelets (clopidogrel, prasugrel and ticagrelor) and anticoagulants (dabigatran, rivaroxaban, apixaban and edoxaban)
Cormac T O’connor, Thomas J Kiernan & Bryan P Yan
Pages: 725-739
Published online: 13 Jun 2017
AbstractforThe genetic basis of antiplatelet and anticoagulant therapy: A pharmacogenetic review of newer antiplatelets (clopidogrel, prasugrel and ticagrelor) and anticoagulants (dabigatran, rivaroxaban, apixaban and edoxaban) | Full Text | References | PDF (1.6 MB)
  • 1191 Views
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Review
The role of membrane transporters in ovarian cancer chemoresistance and prognosis
Ela Cerovska, Katerina Elsnerova, Radka Vaclavikova & Pavel Soucek
Pages: 741-753
Published online: 29 May 2017
AbstractforThe role of membrane transporters in ovarian cancer chemoresistance and prognosis | Full Text | References | PDF (1.2 MB)
  • 280 Views
  • 6 CrossRef citations
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Review
Cardiotoxicity of ErbB2-targeted therapies and its impact on drug development, a spotlight on trastuzumab
Milos Dokmanovic, Kathryn E. King, Nishant Mohan, Yukinori Endo & Wen Jin Wu
Pages: 755-766
Published online: 09 Jun 2017
AbstractforCardiotoxicity of ErbB2-targeted therapies and its impact on drug development, a spotlight on trastuzumab | Full Text | References | PDF (916.5 KB)
  • 527 Views
  • 15 CrossRef citations
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Review
Test systems in drug discovery for hazard identification and risk assessment of human drug-induced liver injury
Industry-led perspective from EFPIA members of the EU Innovative Medicines Initiative Drug Liver Injury Project, MIP DILI
Richard J. Weaver, Catherine Betts, Eric A.G. Blomme, Helga H.J. Gerets, Klaus Gjervig Jensen, Philip G. Hewitt, Satu Juhila, Gilles Labbe, Michael J. Liguori, Natalie Mesens, Monday O. Ogese, Mikael Persson, Jan Snoeys, James L. Stevens, Tracy Walker & B. Kevin Park
Pages: 767-782
Published online: 28 Jun 2017
AbstractforTest systems in drug discovery for hazard identification and risk assessment of human drug-induced liver injury | Full Text | References | PDF (2 MB)
  • 1313 Views
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Drug Evaluation

Article
Efficacy, pharmacokinetic and pharmacodynamic evaluation of apaziquone in the treatment of non-muscle invasive bladder cancer
R. M. Phillips, H. R. Hendriks, J. B. Sweeney, G. Reddy & G. J. Peters
Pages: 783-791
Published online: 03 Jul 2017
AbstractforEfficacy, pharmacokinetic and pharmacodynamic evaluation of apaziquone in the treatment of non-muscle invasive bladder cancer | Full Text | References | PDF (879.8 KB)
  • 2302 Views
  • 20 CrossRef citations
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Open Access
Article
Pharmacokinetic drug evaluation of budesonide in the treatment of Crohn’s disease
Lukasz Kwapisz, Vipul Jairath, Reena Khanna & Brian Feagan
Pages: 793-801
Published online: 16 Jun 2017
AbstractforPharmacokinetic drug evaluation of budesonide in the treatment of Crohn’s disease | Full Text | References | PDF (805.4 KB)
  • 667 Views
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