Expert Opinion on Drug Metabolism & Toxicology, Volume 16, Issue 10 (2020)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 16, Issue 10 (2020)

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Drug Evauluation

Article
Brivaracetam for the treatment of focal-onset seizures: pharmacokinetic and pharmacodynamic evaluations
Stefano de Biase, Gian Luigi Gigli & Mariarosaria Valente
Pages: 853-863
Published online: 20 Sep 2020
AbstractforBrivaracetam for the treatment of focal-onset seizures: pharmacokinetic and pharmacodynamic evaluations | Full Text | References | PDF (308.7 KB) | EPUB
  • 258 Views
  • 3 CrossRef citations
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Review

Genetic factors in anthracycline-induced cardiotoxicity in patients treated for pediatric cancer
Kateryna Petrykey, Gregor U. Andelfinger, Caroline Laverdière, Daniel Sinnett & Maja Krajinovic
Pages: 865-883
Published online: 24 Sep 2020
AbstractforGenetic factors in anthracycline-induced cardiotoxicity in patients treated for pediatric cancer | Full Text | References | PDF (3 MB) | EPUB | Supplemental
  • 409 Views
  • 8 CrossRef citations
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Prodrugs and nanomicelles to overcome ocular barriers for drug penetration
Vrinda Gote, Michael Ansong & Dhananjay Pal
Pages: 885-906
Published online: 23 Aug 2020
AbstractforProdrugs and nanomicelles to overcome ocular barriers for drug penetration | Full Text | References | PDF (7.2 MB) | EPUB
  • 396 Views
  • 36 CrossRef citations
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Diversity of dose-individualization and therapeutic drug monitoring practices of platinum compounds: a review
Maud Maillard, Félicien Le Louedec, Fabienne Thomas & Etienne Chatelut
Pages: 907-925
Published online: 05 Oct 2020
AbstractforDiversity of dose-individualization and therapeutic drug monitoring practices of platinum compounds: a review | Full Text | References | PDF (1.2 MB) | EPUB
  • 275 Views
  • 3 CrossRef citations
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Clinically relevant endothelial nitric oxide synthase polymorphisms and their impact on drug response
Cezar Kayzuka Cotta Filho, Gustavo Henrique Oliveira-Paula, Vitória Carolina Rondon Pereira & Riccardo Lacchini
Pages: 927-951
Published online: 29 Aug 2020
AbstractforClinically relevant endothelial nitric oxide synthase polymorphisms and their impact on drug response | Full Text | References | PDF (652.8 KB) | EPUB
  • 170 Views
  • 13 CrossRef citations
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Pharmacogenetic factors affecting β-blocker metabolism and response
Cameron D. Thomas & Julie A. Johnson
Pages: 953-964
Published online: 09 Sep 2020
AbstractforPharmacogenetic factors affecting β-blocker metabolism and response | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
  • 582 Views
  • 13 CrossRef citations
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Strategies to reduce the risk of platinum containing antineoplastic drug-induced ototoxicity
Debashree Mukherjea, Asmita Dhukhwa, Amit Sapra, Priyanka Bhandari, Katlyn Woolford, Jacob Franke, Vickram Ramkumar & Leonard Rybak
Pages: 965-982
Published online: 29 Sep 2020
AbstractforStrategies to reduce the risk of platinum containing antineoplastic drug-induced ototoxicity | Full Text | References | PDF (1.7 MB) | EPUB
  • 326 Views
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Pharmacokinetic considerations about antiseizure medications in the elderly
Roberta Roberti, Caterina Palleria, Valentina Nesci, Martina Tallarico, Carlo Di Bonaventura, Emanuele Cerulli Irelli, Alessandra Morano, Giovambattista De Sarro, Emilio Russo, Rita Citraro & Antiseizure Medications Commission of the Italian League against Epilepsy (LICE)
Pages: 983-995
Published online: 25 Sep 2020
AbstractforPharmacokinetic considerations about antiseizure medications in the elderly | Full Text | References | PDF (434.7 KB) | EPUB
  • 489 Views
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Original Research

Article
A randomized Phase I pharmacokinetic trial comparing the potential biosimilar trastuzumab (SIBP-01) with the reference product (Herceptin®) in healthy Chinese male volunteers
Huan Zhou, Shugang Cao, Xingyu Zhu, Jing Xie, Ling Fan, Qin Ge, Ying Wang, Juan Zhu, Yuanyuan Liu, ZhongHuan Shao, Rongfang Shan, Bingyan Liu, Hongju Wang & Li Ding
Pages: 997-1003
Published online: 26 Aug 2020
AbstractforA randomized Phase I pharmacokinetic trial comparing the potential biosimilar trastuzumab (SIBP-01) with the reference product (Herceptin®) in healthy Chinese male volunteers | Full Text | References | PDF (584.2 KB) | EPUB
  • 2203 Views
  • 5 CrossRef citations
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