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Volume 16, Issue 5

Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 16, Issue 5 (2020)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 16, Issue 5 (2020)

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Editorial

How do the pharmacokinetics of drugs change in astronauts in space?

Sara Eyal

Pages: 353-356

Published online: 29 Mar 2020

First Page PreviewforHow do the pharmacokinetics of drugs change in astronauts in space? | Full Text | References | PDF (483.6 KB) | EPUB

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Free Access

Review

MDMA interactions with pharmaceuticals and drugs of abuse

Esther Papaseit, Clara Pérez-Mañá, Marta Torrens, Adriana Farré, Lourdes Poyatos, Olga Hladun, Arantza Sanvisens, Roberto Muga & Magi Farré

Pages: 357-369

Published online: 12 Apr 2020

AbstractforMDMA interactions with pharmaceuticals and drugs of abuse | Full Text | References | PDF (1.4 MB) | EPUB

1513 Views
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Review

Pharmacokinetics of current and emerging treatments for hypercholesterolemia

Brian Tomlinson, Paul Chan, Yuzhen Zhang, Zhongmin Liu & Christopher Wai Kei Lam

Pages: 371-385

Published online: 10 Apr 2020

AbstractforPharmacokinetics of current and emerging treatments for hypercholesterolemia | Full Text | References | PDF (1.7 MB) | EPUB

641 Views
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Review

Transporter–enzyme interplay and the hepatic drug clearance: what have we learned so far?

Ravindra V. Alluri, Rui Li & Manthena V. S. Varma

Pages: 387-401

Published online: 12 Apr 2020

AbstractforTransporter–enzyme interplay and the hepatic drug clearance: what have we learned so far? | Full Text | References | PDF (1.5 MB) | EPUB

770 Views
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Review

Pharmacokinetics and pharmacodynamics of levodopa/carbidopa cotherapies for Parkinson’s disease

Thomas Müller

Pages: 403-414

Published online: 27 Apr 2020

AbstractforPharmacokinetics and pharmacodynamics of levodopa/carbidopa cotherapies for Parkinson’s disease | Full Text | References | PDF (1.1 MB) | EPUB

1213 Views
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Review

Pharmacokinetic and pharmacodynamic considerations in antimicrobial therapy for sepsis

Motoki Fujii, Toshiyuki Karumai, Ryohei Yamamoto, Eri Kobayashi, Kenta Ogawa, Mayuko Tounai, Jeffrey Lipman & Yoshiro Hayashi

Pages: 415-430

Published online: 17 Apr 2020

AbstractforPharmacokinetic and pharmacodynamic considerations in antimicrobial therapy for sepsis | Full Text | References | PDF (1.8 MB) | EPUB

591 Views
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Review

The impact of pregnancy on the pharmacokinetics of antidepressants: a systematic critical review and meta-analysis

Georgios Schoretsanitis, Olav Spigset, Julia C. Stingl, Kristina M. Deligiannidis, Michael Paulzen & Andreas A. Westin

Pages: 431-440

Published online: 10 Apr 2020

1025 Views
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Original Research

Article

Assessment of the genotoxic potential of a migraine-specific drug by comet and cytokinesis-block micronucleus assays

Akin Cayir, Hayal Cobanoglu & Munevver Coskun

Pages: 441-446

Published online: 10 Apr 2020

AbstractforAssessment of the genotoxic potential of a migraine-specific drug by comet and cytokinesis-block micronucleus assays | Full Text | References | PDF (612.2 KB) | EPUB

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