Expert Opinion on Drug Metabolism & Toxicology, Volume 20, Issue 1-2 (2024)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 20, Issue 1-2 (2024)

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Editorial

Editorial
Potential benefits and possible risks of CGRP-targeted multitherapy in migraine
Keiko Ihara, Tsubasa Takizawa, Narumi Watanabe, Jin Nakahara & Paolo Martelletti
Pages: 1-4
Published online: 12 Feb 2024
First Page PreviewforPotential benefits and possible risks of CGRP-targeted multitherapy in migraine | Full Text | References | PDF (175.8 KB) | EPUB
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Editorial
What is the risk of hepatotoxicity induced by immune-checkpoint inhibitors and how can we avoid it?
Elisa Tassinari, Matteo Rosellini, Andrea Marchetti, Veronica Mollica & Francesco Massari
Pages: 5-8
Published online: 05 Feb 2024
First Page PreviewforWhat is the risk of hepatotoxicity induced by immune-checkpoint inhibitors and how can we avoid it? | Full Text | References | PDF (1.1 MB) | EPUB
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Review

Review Article
Regulation of PXR in drug metabolism: chemical and structural perspectives
Rebecca R. Florke Gee, Andrew D. Huber & Taosheng Chen
Pages: 9-23
Published online: 28 Jan 2024
AbstractforRegulation of PXR in drug metabolism: chemical and structural perspectives | Full Text | References | PDF (5.5 MB) | EPUB
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Review Article
Comparison of pharmacokinetic properties of alteplase and tenecteplase. The future of thrombolysis in acute ischemic stroke
Alessandro Marè, Simone Lorenzut, Francesco Janes, Carolina Gentile, Roberto Marinig, Yan Tereshko, Gian Luigi Gigli, Mariarosaria Valente & Giovanni Merlino
Pages: 25-36
Published online: 29 Feb 2024
AbstractforComparison of pharmacokinetic properties of alteplase and tenecteplase. The future of thrombolysis in acute ischemic stroke | Full Text | References | PDF (1.8 MB) | EPUB
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Review Article
Interindividual variability in statin pharmacokinetics and effects of drug transporters
Takeshi Hirota & Ichiro Ieiri
Pages: 37-43
Published online: 22 Jan 2024
AbstractforInterindividual variability in statin pharmacokinetics and effects of drug transporters | Full Text | References | PDF (244.7 KB) | EPUB
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Review Article
Pharmacokinetics and pharmacodynamics of antibody-drug conjugates for the treatment of patients with breast cancer
François Cherifi, Angélique Da Silva, Diogo Martins-Branco, Ahmad Awada & Guilherme Nader-Marta
Pages: 45-59
Published online: 12 Jan 2024
AbstractforPharmacokinetics and pharmacodynamics of antibody-drug conjugates for the treatment of patients with breast cancer | Full Text | References | PDF (694.4 KB) | EPUB
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Review Article
Inositols in treating polycystic ovary syndrome and non-insulin dependent diabetes mellitus: now and the future
Antonio Simone Laganà, Samuel H. Myers, Gianpiero Forte, Antoine Naem, Harald Krentel, Leila Allahqoli, Ibrahim Alkatout & Vittorio Unfer
Pages: 61-72
Published online: 22 Jan 2024
AbstractforInositols in treating polycystic ovary syndrome and non-insulin dependent diabetes mellitus: now and the future | Full Text | References | PDF (293.7 KB) | EPUB
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Review Article
The impact of pregnancy and associated hormones on the pharmacokinetics of Δ9-tetrahydrocannabinol
Aurora K. Authement & Nina Isoherranen
Pages: 73-93
Published online: 04 Mar 2024
AbstractforThe impact of pregnancy and associated hormones on the pharmacokinetics of Δ9-tetrahydrocannabinol | Full Text | References | PDF (758.9 KB) | EPUB
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Review Article
Chronic kidney disease and physiologically based pharmacokinetic modeling: a critical review of existing models
Ammara Zamir, Faleh Alqahtani & Muhammad Fawad Rasool
Pages: 95-105
Published online: 31 Jan 2024
AbstractforChronic kidney disease and physiologically based pharmacokinetic modeling: a critical review of existing models | Full Text | References | PDF (937 KB) | EPUB | Supplemental
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