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Expert Opinion on Drug Metabolism & Toxicology
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Volume 3, Issue 3

Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 3, Issue 3 (2007)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 3, Issue 3 (2007)

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Editorial

Article

The impact of advancing age on P-glycoprotein expression and activity: current knowledge and future directions

Arduino A Mangoni

Pages: 315-320

Published online: 31 May 2007

AbstractforThe impact of advancing age on P-glycoprotein expression and activity: current knowledge and future directions | Full Text | References | PDF (78.4 KB)

186 Views
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Perspective

Article

In vitro approaches to investigate mechanism-based inactivation of CYP enzymes

Thomas M Polasek & John O Miners

Pages: 321-329

Published online: 31 May 2007

AbstractforIn vitro approaches to investigate mechanism-based inactivation of CYP enzymes | Full Text | References | PDF (215.4 KB)

492 Views
57 CrossRef citations
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Review

Article

The fate and effects of xenobiotics in human placenta

Päivi Myllynen, Markku Pasanen & Kirsi Vähäkangas

Pages: 331-346

Published online: 31 May 2007

AbstractforThe fate and effects of xenobiotics in human placenta | Full Text | References | PDF (171.1 KB)

457 Views
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Article

Indinavir/ritonavir remains an important component of HAART for the treatment of HIV/AIDS, particularly in resource-limited settings

Tim R Cressey, Nottasorn Plipat, Federica Fregonese & Kulkanya Chokephaibulkit

Pages: 347-361

Published online: 31 May 2007

AbstractforIndinavir/ritonavir remains an important component of HAART for the treatment of HIV/AIDS, particularly in resource-limited settings | Full Text | References | PDF (165.7 KB)

65 Views
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Article

Molecular mechanisms of drug resistance in acute myeloid leukaemia

Donal P McLornan, Mary Frances McMullin, Patrick Johnston & Daniel B Longley

Pages: 363-377

Published online: 31 May 2007

AbstractforMolecular mechanisms of drug resistance in acute myeloid leukaemia | Full Text | References | PDF (339.2 KB)

143 Views
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Article

Improving metabolic stability of cancer chemoprotective polyphenols

Thomas Walle, Xia Wen & U Kristina Walle

Pages: 379-388

Published online: 31 May 2007

AbstractforImproving metabolic stability of cancer chemoprotective polyphenols | Full Text | References | PDF (196.2 KB)

157 Views
27 CrossRef citations
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Article

Natural polyphenol disposition via coupled metabolic pathways

Zhongqiu Liu & Ming Hu

Pages: 389-406

Published online: 31 May 2007

AbstractforNatural polyphenol disposition via coupled metabolic pathways | Full Text | References | PDF (775.3 KB)

250 Views
112 CrossRef citations
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Article

Drug metabolite profiling and elucidation of drug-induced hepatotoxicity

Wei Tang

Pages: 407-420

Published online: 31 May 2007

AbstractforDrug metabolite profiling and elucidation of drug-induced hepatotoxicity | Full Text | References | PDF (162 KB)

552 Views
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Article

The use of glutathione transferase-knockout mice as pharmacological and toxicological models

Philip G Board

Pages: 421-433

Published online: 31 May 2007

AbstractforThe use of glutathione transferase-knockout mice as pharmacological and toxicological models | Full Text | References | PDF (174.9 KB)

163 Views
18 CrossRef citations
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Drug Evaluation

Article

Transdermal oxybutynin: a review

Greg L Shaw & Hiten RH Patel

Pages: 435-439

Published online: 31 May 2007

AbstractforTransdermal oxybutynin: a review | Full Text | References | PDF (66.9 KB)

139 Views
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Article

Ezetimibe: an update on the mechanism of action, pharmacokinetics and recent clinical trials

Mary Ellen Sweeney & Rebecca R Johnson

Pages: 441-450

Published online: 31 May 2007

AbstractforEzetimibe: an update on the mechanism of action, pharmacokinetics and recent clinical trials | Full Text | References | PDF (131.8 KB)

730 Views
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Article

Chronic sildenafil in men with diabetes and erectile dysfunction

Antonio Aversa, Roberto Bruzziches, Cristiana Vitale, Giuseppe Marazzi, Davide Francomano, Giuseppe Barbaro, Giovanni Spera & Giuseppe MC Rosano

Pages: 451-464

Published online: 31 May 2007

AbstractforChronic sildenafil in men with diabetes and erectile dysfunction | Full Text | References | PDF (194.1 KB)

136 Views
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