Expert Opinion on Drug Metabolism & Toxicology, Volume 6, Issue 6 (2010)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 6, Issue 6 (2010)

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Reviews

Article
Human CYPs involved in drug metabolism: structures, substrates and binding affinities
David FV Lewis & Yuko Ito
Pages: 661-674
Published online: 19 Apr 2010
AbstractforHuman CYPs involved in drug metabolism: structures, substrates and binding affinities | Full Text | References | PDF (705.4 KB)
  • 550 Views
  • 43 CrossRef citations
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Article
A role for CYP in the drug–hormone crosstalk of the brain
Ralf Peter Meyer PhD & Marcel Gehlhaus
Pages: 675-687
Published online: 05 Mar 2010
AbstractforA role for CYP in the drug–hormone crosstalk of the brain | Full Text | References | PDF (460.4 KB)
  • 103 Views
  • 7 CrossRef citations
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Article
Altered drug metabolism during pregnancy: hormonal regulation of drug-metabolizing enzymes
Hyunyoung Jeong PharmD PhD
Pages: 689-699
Published online: 05 Apr 2010
AbstractforAltered drug metabolism during pregnancy: hormonal regulation of drug-metabolizing enzymes | Full Text | References | PDF (309.4 KB)
  • 866 Views
  • 117 CrossRef citations
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Article
Anti-HIV therapy with AZT prodrugs: AZT phosphonate derivatives, current state and prospects
Anastasiya Khandazhinskaya, Elena Matyugina & Elena Shirokova
Pages: 701-714
Published online: 09 Apr 2010
AbstractforAnti-HIV therapy with AZT prodrugs: AZT phosphonate derivatives, current state and prospects | Full Text | References | PDF (561.9 KB)
  • 352 Views
  • 29 CrossRef citations
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Article
Online electrochemistry/mass spectrometry in drug metabolism studies: principles and applications
Anne Baumann & Uwe Karst
Pages: 715-731
Published online: 07 Apr 2010
AbstractforOnline electrochemistry/mass spectrometry in drug metabolism studies: principles and applications | Full Text | References | PDF (459.8 KB)
  • 489 Views
  • 87 CrossRef citations
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Article
Three-dimensional culture of hepatocytes for prediction of drug-induced hepatotoxicity
Qin Meng
Pages: 733-746
Published online: 09 Apr 2010
AbstractforThree-dimensional culture of hepatocytes for prediction of drug-induced hepatotoxicity | Full Text | References | PDF (335.4 KB)
  • 1373 Views
  • 99 CrossRef citations
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Article
Predictive tools for the evaluation of microbial effects on drugs during gastrointestinal passage
Ines A Pieper & Martin Bertau
Pages: 747-760
Published online: 02 Apr 2010
AbstractforPredictive tools for the evaluation of microbial effects on drugs during gastrointestinal passage | Full Text | References | PDF (472.2 KB)
  • 165 Views
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Article
Using drug probes to monitor hepatic drug metabolism in critically ill patients: midazolam, a flawed but useful tool for clinical investigation of CYP3A activity?
Chris Kirwan (SpR in Renal Medicine) BSc MBBS MRCP, Iain MacPhee (Reader in Renal Medicine) BSc DPhil BM BCh FRCP & Barbara Philips (Senior Lecturer Intensive Care Medicine) BSc MBBS FRCA MD DICM
Pages: 761-771
Published online: 19 Apr 2010
AbstractforUsing drug probes to monitor hepatic drug metabolism in critically ill patients: midazolam, a flawed but useful tool for clinical investigation of CYP3A activity? | Full Text | References | PDF (313.2 KB)
  • 322 Views
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Drug Evaluation

Article
Pharmacologic evaluation of ospemifene
Jamie L McCall (Graduate Student in Pharmacology and Toxicology) MS & Michael W DeGregorio (Professor of Medicine) PharmD
Pages: 773-779
Published online: 29 Apr 2010
AbstractforPharmacologic evaluation of ospemifene | Full Text | References | PDF (237.6 KB)
  • 250 Views
  • 21 CrossRef citations
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