Expert Opinion on Drug Metabolism & Toxicology, Volume 7, Issue 4 (2011)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 7, Issue 4 (2011)

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Editorial

Article
Maximizing the outcome of early ADMET models: strategies to win the drug-hunting battles?
Jianling Wang (Head of ADME Profiling Cambridge) & Alan Collis
Pages: 381-386
Published online: 19 Mar 2011
AbstractforMaximizing the outcome of early ADMET models: strategies to win the drug-hunting battles? | Full Text | References | PDF (354.3 KB) | Supplemental
  • 209 Views
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Reviews

Article
The impact of cholesterol and its metabolites on drug metabolism
Tadeja Režen
Pages: 387-398
Published online: 15 Feb 2011
AbstractforThe impact of cholesterol and its metabolites on drug metabolism | Full Text | References | PDF (369.6 KB)
  • 281 Views
  • 9 CrossRef citations
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Article
Toxicological considerations for antithyroid drugs in children
Spiros Karras MD, Themistoklis Tzotzas MD PhD & Gerasimos E Krassas (Chairman) MD PhD FRCP(Lond)
Pages: 399-410
Published online: 17 Feb 2011
AbstractforToxicological considerations for antithyroid drugs in children | Full Text | References | PDF (260.3 KB)
  • 463 Views
  • 8 CrossRef citations
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Article
Genetic variations of bile salt transporters as predisposing factors for drug-induced cholestasis, intrahepatic cholestasis of pregnancy and therapeutic response of viral hepatitis
Bruno Stieger PhD & Andreas Geier
Pages: 411-425
Published online: 15 Feb 2011
AbstractforGenetic variations of bile salt transporters as predisposing factors for drug-induced cholestasis, intrahepatic cholestasis of pregnancy and therapeutic response of viral hepatitis | Full Text | References | PDF (362.9 KB)
  • 598 Views
  • 46 CrossRef citations
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Article
The pharmacokinetic evaluation of artemisinin drugs for the treatment of malaria in paediatric populations
Amy E Mercer & Mariama Sarr Sallah
Pages: 427-439
Published online: 15 Feb 2011
AbstractforThe pharmacokinetic evaluation of artemisinin drugs for the treatment of malaria in paediatric populations | Full Text | References | PDF (428.1 KB)
  • 218 Views
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Article
Novel therapy in Parkinson's disease: adenosine A2A receptor antagonists
Nikoletta Szabó, Zsigmond Tamás Kincses & László Vécsei (Professor, Director)
Pages: 441-455
Published online: 19 Feb 2011
AbstractforNovel therapy in Parkinson's disease: adenosine A2A receptor antagonists | Full Text | References | PDF (307.8 KB)
  • 522 Views
  • 24 CrossRef citations
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Article
Approaches for understanding and predicting drug interactions in human immunodeficiency virus-infected patients
Inmaculada Jiménez-Nácher, Elena Alvarez, Judit Morello, Sonia Rodriguez-Nóvoa, Susana de Andrés & Vincent Soriano
Pages: 457-477
Published online: 23 Feb 2011
AbstractforApproaches for understanding and predicting drug interactions in human immunodeficiency virus-infected patients | Full Text | References | PDF (253.2 KB)
  • 409 Views
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Drug Evaluations

Article
Eritoran tetrasodium (E5564) treatment for sepsis: review of preclinical and clinical studies
Amisha Barochia MBBS, Steven Solomon, Xizhong Cui, Charles Natanson & Peter Q Eichacker
Pages: 479-494
Published online: 17 Feb 2011
AbstractforEritoran tetrasodium (E5564) treatment for sepsis: review of preclinical and clinical studies | Full Text | References | PDF (578.2 KB)
  • 647 Views
  • 123 CrossRef citations
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Article
Nevirapine once daily: pharmacology, metabolic profile and efficacy data of the new extended-release formulation
Jean-Jacques Parienti MD PhD & Gilles Peytavin PharmD PhD
Pages: 495-503
Published online: 20 Mar 2011
AbstractforNevirapine once daily: pharmacology, metabolic profile and efficacy data of the new extended-release formulation | Full Text | References | PDF (353.5 KB)
  • 216 Views
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Article
Pharmacokinetic evaluation of palifermin for mucosal protection from chemotherapy and radiation
Christian Weigelt, Rainer Haas & Guido Kobbe (Head of the Bone Marrow Transplantation Unit)
Pages: 505-515
Published online: 19 Mar 2011
AbstractforPharmacokinetic evaluation of palifermin for mucosal protection from chemotherapy and radiation | Full Text | References | PDF (275.4 KB)
  • 314 Views
  • 7 CrossRef citations
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Article
Clinical utilization of cinacalcet in hypercalcemic conditions
Piergiorgio Messa MD, Carlo Alfieri PhD & Brigida Brezzi MD
Pages: 517-528
Published online: 01 Mar 2011
AbstractforClinical utilization of cinacalcet in hypercalcemic conditions | Full Text | References | PDF (260.4 KB)
  • 345 Views
  • 12 CrossRef citations
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