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Volume 9, Issue 12

Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 9, Issue 12 (2013)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 9, Issue 12 (2013)

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Reviews

Review Article

The evolution of our understanding of endo-xenobiotic crosstalk and cytochrome P450 regulation and the therapeutic implications

Tewes Tralau & Andreas Luch

Pages: 1541-1554

Published online: 13 Aug 2013

AbstractforThe evolution of our understanding of endo-xenobiotic crosstalk and cytochrome P450 regulation and the therapeutic implications | Full Text | References | PDF (612.5 KB)

277 Views
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Review Article

Gender-dependent differences in uridine 5'-diphospho-glucuronosyltransferase have implications in metabolism and clearance of xenobiotics

Wei Liu, Kaustubh Kulkarni & Ming Hu

Pages: 1555-1569

Published online: 06 Sep 2013

AbstractforGender-dependent differences in uridine 5'-diphospho-glucuronosyltransferase have implications in metabolism and clearance of xenobiotics | Full Text | References | PDF (622 KB)

397 Views
10 CrossRef citations
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Review Article

In vitro drug metabolism testing using blood-monocyte derivatives

Guillermo Gómez-Icazbalceta, Ignacio González-Sánchez, José Moreno, Marco A Cerbón & Alicia Cervantes

Pages: 1571-1580

Published online: 29 Aug 2013

AbstractforIn vitro drug metabolism testing using blood-monocyte derivatives | Full Text | References | PDF (398.6 KB)

231 Views
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Review Article

Lipid-like properties and pharmacology of the anthelmintic macrocyclic lactones

Anne Lespine

Pages: 1581-1595

Published online: 19 Sep 2013

AbstractforLipid-like properties and pharmacology of the anthelmintic macrocyclic lactones | Full Text | References | PDF (545.8 KB)

251 Views
13 CrossRef citations
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Review Article

Small molecule kinase inhibitors approved by the FDA from 2000 to 2011: a systematic review of preclinical ADME data

Zhihong O'Brien & Mehran Fallah Moghaddam

Pages: 1597-1612

Published online: 31 Aug 2013

AbstractforSmall molecule kinase inhibitors approved by the FDA from 2000 to 2011: a systematic review of preclinical ADME data | Full Text | References | PDF (612.4 KB)

1245 Views
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Review Article

Keratoconus and crosslinking: pharmacokinetic considerations

Clara C Chan MD FRCSC FACS & Victoria Squissato MSc HBSc

Pages: 1613-1624

Published online: 04 Sep 2013

AbstractforKeratoconus and crosslinking: pharmacokinetic considerations | Full Text | References | PDF (373.8 KB)

291 Views
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Review Article

Pharmacogenetic considerations for non-Hodgkin's lymphoma therapy

Ana Espirito Santo MD & Rui Medeiros PhD

Pages: 1625-1634

Published online: 22 Sep 2013

AbstractforPharmacogenetic considerations for non-Hodgkin's lymphoma therapy | Full Text | References | PDF (495.7 KB)

141 Views
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Review Article

Vehicle selection for nonclinical oral safety studies

Evan A Thackaberry PhD DABT

Pages: 1635-1646

Published online: 27 Sep 2013

AbstractforVehicle selection for nonclinical oral safety studies | Full Text | References | PDF (437.4 KB)

1946 Views
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Drug Evaluations

The pharmacokinetic evaluation of boceprevir for treatment of Hepatitis C virus

Hari Shankar, Kian Bichoupan & Douglas T Dieterich

Pages: 1647-1657

Published online: 01 Oct 2013

AbstractforThe pharmacokinetic evaluation of boceprevir for treatment of Hepatitis C virus | Full Text | References | PDF (692.6 KB)

284 Views
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Evaluation of fesoterodine fumarate for the treatment of an overactive bladder

Stephen Mock MD & Roger R Dmochowski MD

Pages: 1659-1666

Published online: 09 Nov 2013

AbstractforEvaluation of fesoterodine fumarate for the treatment of an overactive bladder | Full Text | References | PDF (524.1 KB)

265 Views
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Eltrombopag for the treatment of thrombocytopenia in patients with malignant and non-malignant hematologic disorders

Swati Pathak, Michael Roth, Amit Verma & Ulrich Steidl

Pages: 1667-1675

Published online: 12 Nov 2013

Abstractfor Eltrombopag for the treatment of thrombocytopenia in patients with malignant and non-malignant hematologic disorders | Full Text | References | PDF (393.2 KB)

609 Views
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Letter to the Editor

Letter

Comment on: Dogs and monkeys in preclinical drug development: the challenge of reducing and replacing

Jeffrey Brown (Advisor)

Pages: 1677-1678

Published online: 09 Nov 2013

CitationforComment on: Dogs and monkeys in preclinical drug development: the challenge of reducing and replacing | Full Text | References | PDF (186.3 KB)

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Free Access

Research Article

Article

Page: i

Published online: 15 Nov 2013

39 Views
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