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Volume 9, Issue 3

Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 9, Issue 3 (2013)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 9, Issue 3 (2013)

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Reviews

Review Article

Species differences in drug transporters and implications for translating preclinical findings to humans

Xiaoyan Chu, Kelly Bleasby & Raymond Evers

Pages: 237-252

Published online: 21 Dec 2012

AbstractforSpecies differences in drug transporters and implications for translating preclinical findings to humans | Full Text | References | PDF (392.3 KB)

5358 Views
228 CrossRef citations
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Review Article

Nuclear receptors PXR and CAR: implications for drug metabolism regulation, pharmacogenomics and beyond

Xiaojuan Chai, Su Zeng & Wen Xie

Pages: 253-266

Published online: 17 Jan 2013

AbstractforNuclear receptors PXR and CAR: implications for drug metabolism regulation, pharmacogenomics and beyond | Full Text | References | PDF (478.7 KB)

1340 Views
121 CrossRef citations
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Review Article

The effects of flavonoids on the ABC transporters: consequences for the pharmacokinetics of substrate drugs

Yan Li (Senior Lecturer) PhD & James W Paxton (Associate-Professor) PhD

Pages: 267-285

Published online: 06 Jan 2013

AbstractforThe effects of flavonoids on the ABC transporters: consequences for the pharmacokinetics of substrate drugs | Full Text | References | PDF (448.2 KB)

525 Views
33 CrossRef citations
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Review Article

Effect of the ATP-binding cassette transporter ABCG2 on pharmacokinetics: experimental findings and clinical implications

Rebecca Schnepf & Oliver Zolk

Pages: 287-306

Published online: 07 Jan 2013

AbstractforEffect of the ATP-binding cassette transporter ABCG2 on pharmacokinetics: experimental findings and clinical implications | Full Text | References | PDF (683 KB)

489 Views
25 CrossRef citations
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Review Article

Metabolic differences of current thienopyridine antiplatelet agents

Jawed Fareed PhD, Walter Jeske & Indermohan Thethi MD

Pages: 307-317

Published online: 06 Jan 2013

AbstractforMetabolic differences of current thienopyridine antiplatelet agents | Full Text | References | PDF (388.4 KB)

354 Views
8 CrossRef citations
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Review Article

The role of sphingolipids in drug metabolism and transport

Young Mi Kim, Tae-Sik Park & Sang Geon Kim PhD

Pages: 319-331

Published online: 07 Jan 2013

AbstractforThe role of sphingolipids in drug metabolism and transport | Full Text | References | PDF (501.1 KB)

306 Views
3 CrossRef citations
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Review Article

Pharmacology of dimethanesulfonate alkylating agents: busulfan and treosulfan

Ariane Galaup & Angelo Paci

Pages: 333-347

Published online: 16 Nov 2012

AbstractforPharmacology of dimethanesulfonate alkylating agents: busulfan and treosulfan | Full Text | References | PDF (375 KB)

805 Views
48 CrossRef citations
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Review Article

Crystal structure of arylamine N-acetyltransferases: insights into the mechanisms of action and substrate selectivity

Xavier Kubiak PhD, Julien Dairou (Assistant professor) PhD, Jean-Marie Dupret (Professor, Head of the lab) PhD & Fernando Rodrigues-Lima (Professor) PhD

Pages: 349-362

Published online: 07 Jan 2013

AbstractforCrystal structure of arylamine N-acetyltransferases: insights into the mechanisms of action and substrate selectivity | Full Text | References | PDF (1 MB)

247 Views
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Drug Evaluations

Article

Linagliptin plus metformin: a pharmacokinetic and pharmacodynamic evaluation

André J Scheen (Professor)

Pages: 363-377

Published online: 04 Feb 2013

Abstractfor Linagliptin plus metformin: a pharmacokinetic and pharmacodynamic evaluation | Full Text | References | PDF (385.5 KB)

665 Views
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Article

Pharmacokinetic evaluation and clinical utility of azilsartan medoxomil for the treatment of hypertension

Fabio Angeli MD, Paolo Verdecchia MD, FACC, FESH, FAHA, Chiara Pascucci MD, Cristina Poltronieri MD & Gianpaolo Reboldi MD PhD MSc

Pages: 379-385

Published online: 07 Feb 2013

AbstractforPharmacokinetic evaluation and clinical utility of azilsartan medoxomil for the treatment of hypertension | Full Text | References | PDF (335.1 KB)

563 Views
21 CrossRef citations
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Research Article

Article

Page: i

Published online: 18 Feb 2013

292 Views
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Open Access

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Recent progress in machine learning approaches for predicting carcinogenicity in drug development

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The role of the circadian timing system on drug metabolism and detoxification: an update

Alper Okyar et al.

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Expert Opinion on Drug Metabolism & Toxicology (Vol.9, Iss.3, 2013)

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