Expert Opinion on Drug Metabolism & Toxicology, Volume 9, Issue 7 (2013)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 9, Issue 7 (2013)

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Original Research

Article
Development of cardiac safety translational tools for QT prolongation and torsade de pointes
Luis G Valerio Jr (Science and Research Staff) PhD, Suchitra Balakrishnan MD PhD, Monica L Fiszman MD PhD, Devi Kozeli RAC, Mike Li MD, Sarvin Moghaddam (Science and Research Staff) PhD & Nakissa Sadrieh (Science and Research Staff) PhD
Pages: 801-815
Published online: 28 Mar 2013
AbstractforDevelopment of cardiac safety translational tools for QT prolongation and torsade de pointes | Full Text | References | PDF (673.4 KB) | Supplemental
  • 426 Views
  • 17 CrossRef citations
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Reviews

Review Article
Microdosing and drug development: past, present and future
Graham Lappin (Reader in Pharmaceutical Science) PhD, Robert Noveck (Medical Director) MD PhD & Tal Burt (Scientific Director, Assistant Professor) MD
Pages: 817-834
Published online: 04 Apr 2013
AbstractforMicrodosing and drug development: past, present and future | Full Text | References | PDF (295.9 KB)
  • 1117 Views
  • 76 CrossRef citations
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Review Article
Metabolic and toxicological considerations of newly approved prostate cancer drugs
Che-Kai Tsao MD, Bobby Liaw MD, Tiffany Yee, Matthew D Galsky MD & William K Oh MD
Pages: 835-846
Published online: 12 Apr 2013
AbstractforMetabolic and toxicological considerations of newly approved prostate cancer drugs | Full Text | References | PDF (431.5 KB)
  • 474 Views
  • 4 CrossRef citations
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Review Article
An evaluation of the latest evidence relating to renin–angiotensin system inhibitors
Carlos Escobar & Vivencio Barrios
Pages: 847-858
Published online: 08 Apr 2013
AbstractforAn evaluation of the latest evidence relating to renin–angiotensin system inhibitors | Full Text | References | PDF (270.5 KB)
  • 441 Views
  • 5 CrossRef citations
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Review Article
Anti-Parkinson's disease drugs and pharmacogenetic considerations
José A G Agúndez MD PhD, Elena García-Martín, Hortensia Alonso-Navarro & Félix Javier Jiménez-Jiménez
Pages: 859-874
Published online: 09 Apr 2013
AbstractforAnti-Parkinson's disease drugs and pharmacogenetic considerations | Full Text | References | PDF (302.2 KB)
  • 1347 Views
  • 43 CrossRef citations
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Review Article
Pharmacogenetics of drugs used in the treatment of ocular inflammatory diseases
Breno R Lima MD, Robert B Nussenblatt MD MPH & H Nida Sen MD MHS
Pages: 875-882
Published online: 25 Mar 2013
AbstractforPharmacogenetics of drugs used in the treatment of ocular inflammatory diseases | Full Text | References | PDF (240.8 KB)
  • 320 Views
  • 6 CrossRef citations
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Drug Evaluations

Pharmacokinetic evaluation of bazedoxifene for the treatment of osteoporosis
Davide Gatti (Assistant Professor) , Maurizio Rossini (Assistant Professor) , Ignazio Sblendorio MD & Stefano Lello MD PhD
Pages: 883-892
Published online: 27 Apr 2013
AbstractforPharmacokinetic evaluation of bazedoxifene for the treatment of osteoporosis | Full Text | References | PDF (265.6 KB)
  • 343 Views
  • 9 CrossRef citations
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Clinical development of dabrafenib in BRAF mutant melanoma and other malignancies
Geoffrey T Gibney (Assistant Member) MD & Jonathan S Zager (Director of Regional Therapies, Associate Member) MD FACS
Pages: 893-899
Published online: 29 Apr 2013
AbstractforClinical development of dabrafenib in BRAF mutant melanoma and other malignancies | Full Text | References | PDF (242.9 KB)
  • 902 Views
  • 60 CrossRef citations
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Certoparin for the treatment and prevention of thrombosis: pharmacological profile and results from clinical studies
Marco P Donadini, Walter Ageno, Luigina Guasti & Alessandro Squizzato
Pages: 901-909
Published online: 27 Apr 2013
Abstractfor Certoparin for the treatment and prevention of thrombosis: pharmacological profile and results from clinical studies | Full Text | References | PDF (182.4 KB)
  • 119 Views
  • 3 CrossRef citations
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Itraconazole: an update on pharmacology and clinical use for treatment of invasive and allergic fungal infections
Jodi Lestner & William W Hope (Professor)
Pages: 911-926
Published online: 06 May 2013
Abstractfor Itraconazole: an update on pharmacology and clinical use for treatment of invasive and allergic fungal infections | Full Text | References | PDF (484.7 KB)
  • 919 Views
  • 80 CrossRef citations
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Research Article

Article
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Page: i
Published online: 17 Jun 2013
CitationforRelated articles | Full Text | PDF (172.8 KB)
  • 74 Views
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