Expert Opinion on Drug Metabolism & Toxicology, Volume 9, Issue 9 (2013)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 9, Issue 9 (2013)

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Reviews

Review Article
Drug absorption, distribution, metabolism and excretion considerations in critically ill adults
Derek J Roberts (Doctor of Philosophy Student and Resident) BSc (Pharm) MD & Richard I Hall BSc (Pharm) MD FRCPC FCCP
Pages: 1067-1084
Published online: 17 May 2013
AbstractforDrug absorption, distribution, metabolism and excretion considerations in critically ill adults | Full Text | References | PDF (380.8 KB)
  • 1209 Views
  • 67 CrossRef citations
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Review Article
Hormone-related pharmacokinetic variations associated with anti-breast cancer drugs
Juan Li, Zhiguo Ma, Ren-wang Jiang & Baojian Wu PhD
Pages: 1085-1095
Published online: 20 May 2013
AbstractforHormone-related pharmacokinetic variations associated with anti-breast cancer drugs | Full Text | References | PDF (342.5 KB)
  • 233 Views
  • 5 CrossRef citations
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Review Article
In vitro approaches to investigate cytochrome P450 activities: update on current status and their applicability
Chin Eng Ong PhD, Yan Pan PhD, Joon Wah Mak & Rusli Ismail
Pages: 1097-1113
Published online: 17 May 2013
AbstractforIn vitro approaches to investigate cytochrome P450 activities: update on current status and their applicability | Full Text | References | PDF (413.5 KB)
  • 427 Views
  • 10 CrossRef citations
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Review Article
Considering CYP1A2 phenotype and genotype for optimizing the dose of olanzapine in the management of schizophrenia
Vidya Perera, Annette S Gross, Thomas M Polasek, Yan Qin, Gauri Rao, Alan Forrest, Junzhe Xu (Associate Clinical Professor) & Andrew J McLachlan
Pages: 1115-1137
Published online: 04 May 2013
AbstractforConsidering CYP1A2 phenotype and genotype for optimizing the dose of olanzapine in the management of schizophrenia | Full Text | References | PDF (435.7 KB)
  • 566 Views
  • 32 CrossRef citations
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Review Article
Glycine conjugation: importance in metabolism, the role of glycine N-acyltransferase, and factors that influence interindividual variation
Christoffel Petrus Stephanus Badenhorst (PhD Student) MSc, Rencia van der Sluis (PhD Student/Laboratory Technician) MSc, Elardus Erasmus (Senior Lecturer) MSc & Alberdina Aike van Dijk (Professor) PhD
Pages: 1139-1153
Published online: 08 May 2013
AbstractforGlycine conjugation: importance in metabolism, the role of glycine N-acyltransferase, and factors that influence interindividual variation | Full Text | References | PDF (481.3 KB)
  • 1175 Views
  • 53 CrossRef citations
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Review Article
Advances in the development and use of human tissue-based techniques for drug toxicity testing
Margaret Clotworthy PhD & Kathy Archibald
Pages: 1155-1169
Published online: 20 May 2013
AbstractforAdvances in the development and use of human tissue-based techniques for drug toxicity testing | Full Text | References | PDF (384 KB)
  • 386 Views
  • 2 CrossRef citations
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Review Article
Dogs and monkeys in preclinical drug development: the challenge of reducing and replacing
Mario Pellegatti
Pages: 1171-1180
Published online: 25 May 2013
AbstractforDogs and monkeys in preclinical drug development: the challenge of reducing and replacing | Full Text | References | PDF (344.2 KB)
  • 463 Views
  • 5 CrossRef citations
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Review Article
Advances in the understanding of retinal drug disposition and the role of blood–ocular barrier transporters
Joaquín Jordán PhD & José M Ruíz-Moreno MD PhD
Pages: 1181-1192
Published online: 07 May 2013
AbstractforAdvances in the understanding of retinal drug disposition and the role of blood–ocular barrier transporters | Full Text | References | PDF (275.9 KB)
  • 527 Views
  • 19 CrossRef citations
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Drug Evaluations

Product Review
Pharmacokinetic evaluation of sildenafil as a pulmonary hypertension treatment
Marie-Camille Chaumais PharmD PhD, Swanny Perrin PharmD, Olivier Sitbon MD PhD, Gérald Simonneau MD, Marc Humbert MD PhD & David Montani MD PhD
Pages: 1193-1205
Published online: 12 Jun 2013
AbstractforPharmacokinetic evaluation of sildenafil as a pulmonary hypertension treatment | Full Text | References | PDF (500.8 KB)
  • 695 Views
  • 20 CrossRef citations
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Product Review
Sapropterin dihydrochloride for the treatment of hyperphenylalaninemias
Nenad Blau
Pages: 1207-1218
Published online: 27 May 2013
Abstractfor Sapropterin dihydrochloride for the treatment of hyperphenylalaninemias | Full Text | References | PDF (504.3 KB)
  • 620 Views
  • 41 CrossRef citations
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Product Review
Pharmacokinetic evaluation of nabiximols for the treatment of multiple sclerosis pain
Radu Tanasescu & Cris S Constantinescu
Pages: 1219-1228
Published online: 27 Apr 2013
AbstractforPharmacokinetic evaluation of nabiximols for the treatment of multiple sclerosis pain | Full Text | References | PDF (367.3 KB)
  • 524 Views
  • 7 CrossRef citations
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Product Review
Bupropion for the treatment of seasonal affective disorder
Peter Niemegeers MD, Glenn JH Dumont PhD, Lisbeth Patteet, Hugo Neels PhD & Bernard GC Sabbe MD PhD
Pages: 1229-1240
Published online: 27 May 2013
Abstractfor Bupropion for the treatment of seasonal affective disorder | Full Text | References | PDF (431.2 KB) | Supplemental
  • 417 Views
  • 9 CrossRef citations
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Original Articles

Article
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Page: i
Published online: 14 Aug 2013
CitationforRelated articles | Full Text | PDF (171.8 KB)
  • 40 Views
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