Human Vaccines & Immunotherapeutics, Volume 13, Issue 12 (2017)

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Human Vaccines & Immunotherapeutics, Volume 13, Issue 12 (2017)

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The International Society for Vaccines 2016 Annual Congress, Boston, Oct. 2-4, 2016

Editor's Corner

Editorial
Letter from the editor
Page: 2751
Published online: 05 Dec 2017
CitationforLetter from the editor | Full Text | PDF (107.5 KB)
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News, Policy & Profiles

News
Human Vaccines & Immunotherapeutics: News
Pages: 2752-2753
Published online: 05 Dec 2017
CitationforHuman Vaccines & Immunotherapeutics: News | Full Text | References | PDF (193.2 KB)
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Editorial

Editorial
Introduction to special issue: International Society for Vaccines Annual Congress 2016
Margaret A. Liu & Shan Lu
Page: 2754
Published online: 05 Dec 2017
CitationforIntroduction to special issue: International Society for Vaccines Annual Congress 2016 | Full Text | PDF (133.6 KB)
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Research Papers

Article
Vaccines for epidemic infections and the role of CEPI
Stanley A. Plotkin
Pages: 2755-2762
Published online: 27 Apr 2017
AbstractforVaccines for epidemic infections and the role of CEPI | Full Text | References | PDF (366.6 KB)
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Article
Functionally inactivated dominant viral antigens of human cytomegalovirus delivered in replication incompetent adenovirus type 6 vectors as vaccine candidates
Aimin Tang, Daniel C. Freed, Fengsheng Li, Steve Meschino, Michael Prokop, Andrew Bett, Danilo Casimiro, Dai Wang & Tong-Ming Fu
Pages: 2763-2771
Published online: 11 May 2017
AbstractforFunctionally inactivated dominant viral antigens of human cytomegalovirus delivered in replication incompetent adenovirus type 6 vectors as vaccine candidates | Full Text | References | PDF (832.5 KB) | Supplemental
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Article
Sulfated archaeal glycolipid archaeosomes as a safe and effective vaccine adjuvant for induction of cell-mediated immunity
Michael J. McCluskie, Lise Deschatelets & Lakshmi Krishnan
Pages: 2772-2779
Published online: 09 Jun 2017
AbstractforSulfated archaeal glycolipid archaeosomes as a safe and effective vaccine adjuvant for induction of cell-mediated immunity | Full Text | References | PDF (691.4 KB)
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Commentary

Article Commentary
Detection, phenotyping and quantification of dengue virus-specific B cells using fluorescent probes
Heather Friberg & Anuja Mathew
Pages: 2780-2784
Published online: 16 Jun 2017
AbstractforDetection, phenotyping and quantification of dengue virus-specific B cells using fluorescent probes | Full Text | References | PDF (322.4 KB)
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Research Papers

Article
A trivalent subunit antigen glycoprotein vaccine as immunotherapy for genital herpes in the guinea pig genital infection model
Sita Awasthi, Lauren M. Hook, Carolyn E. Shaw & Harvey M. Friedman
Pages: 2785-2793
Published online: 16 Jun 2017
AbstractforA trivalent subunit antigen glycoprotein vaccine as immunotherapy for genital herpes in the guinea pig genital infection model | Full Text | References | PDF (825.2 KB)
  • 1517 Views
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Article
Mucosal immunization with a flagellin-adjuvanted Hgp44 vaccine enhances protective immune responses in a murine Porphyromonas gingivalis infection model
Sao Puth, Seol Hee Hong, Mi Jin Park, Hye Hwa Lee, Youn Suhk Lee, Kwangjoon Jeong, In-Chol Kang, Jeong Tae Koh, Byounggon Moon, Sang Chul Park, Joon Haeng Rhee & Shee Eun Lee
Pages: 2794-2803
Published online: 30 Oct 2017
AbstractforMucosal immunization with a flagellin-adjuvanted Hgp44 vaccine enhances protective immune responses in a murine Porphyromonas gingivalis infection model | Full Text | References | PDF (1,007.8 KB) | Supplemental
  • 2000 Views
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Article
Safety and long-term immunological effects of CryJ2-LAMP plasmid vaccine in Japanese red cedar atopic subjects: A phase I study
Yan Su, Eliezer Romeu-Bonilla, Athanasia Anagnostou, David Fitz-Patrick, William Hearl & Teri Heiland
Pages: 2804-2813
Published online: 26 Jun 2017
AbstractforSafety and long-term immunological effects of CryJ2-LAMP plasmid vaccine in Japanese red cedar atopic subjects: A phase I study | Full Text | References | PDF (479.5 KB) | Supplemental
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Article
The importance of RSV F protein conformation in VLPs in stimulation of neutralizing antibody titers in mice previously infected with RSV
Lori M. Cullen, Madelyn R. Schmidt & Trudy G. Morrison
Pages: 2814-2823
Published online: 22 Jun 2017
AbstractforThe importance of RSV F protein conformation in VLPs in stimulation of neutralizing antibody titers in mice previously infected with RSV | Full Text | References | PDF (817.3 KB)
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Article
An immunoinformatics-derived DNA vaccine encoding human class II T cell epitopes of Ebola virus, Sudan virus, and Venezuelan equine encephalitis virus is immunogenic in HLA transgenic mice
Callie E. Bounds, Frances E. Terry, Leonard Moise, Drew Hannaman, William D. Martin, Anne S. De Groot, John J. Suschak, Lesley C. Dupuy & Connie S. Schmaljohn
Pages: 2824-2836
Published online: 21 Jul 2017
AbstractforAn immunoinformatics-derived DNA vaccine encoding human class II T cell epitopes of Ebola virus, Sudan virus, and Venezuelan equine encephalitis virus is immunogenic in HLA transgenic mice | Full Text | References | PDF (1.4 MB)
  • 1753 Views
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Review

Review
Advancements in DNA vaccine vectors, non-mechanical delivery methods, and molecular adjuvants to increase immunogenicity
John J. Suschak, James A. Williams & Connie S. Schmaljohn
Pages: 2837-2848
Published online: 05 Jul 2017
AbstractforAdvancements in DNA vaccine vectors, non-mechanical delivery methods, and molecular adjuvants to increase immunogenicity | Full Text | References | PDF (679.4 KB)
  • 7926 Views
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Research Papers

Article
Immunization with HIV-1 envelope T20-encoding DNA vaccines elicits cross-clade neutralizing antibody responses
S. Stenler, K. E. Lundin, L. Hansen, S. Petkov, N. Mozafari, M. Isaguliants, P. Blomberg, C. I. E. Smith, D. M. Goldenberg, C.-H. Chang, K. Ljungberg, J. Hinkula & B. Wahren
Pages: 2849-2858
Published online: 14 Nov 2017
AbstractforImmunization with HIV-1 envelope T20-encoding DNA vaccines elicits cross-clade neutralizing antibody responses | Full Text | References | PDF (841.7 KB) | Supplemental
  • 1242 Views
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Article
HIV Env conserved element DNA vaccine alters immunodominance in macaques
Xintao Hu, Antonio Valentin, Margherita Rosati, Siriphan Manocheewa, Candido Alicea, Bhabadeb Chowdhury, Jenifer Bear, Kate E. Broderick, Niranjan Y. Sardesai, Sylvie Le Gall, James I. Mullins, George N. Pavlakis & Barbara K. Felber
Pages: 2859-2871
Published online: 07 Nov 2017
AbstractforHIV Env conserved element DNA vaccine alters immunodominance in macaques | Full Text | References | PDF (1 MB)
  • 1273 Views
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Article
Enrichment of Ly6Chi monocytes by multiple GM-CSF injections with HBV vaccine contributes to viral clearance in a HBV mouse model
Weidong Zhao, Xian Zhou, Gan Zhao, Qing Lin, Xianzheng Wang, Xueping Yu & Bin Wang
Pages: 2872-2882
Published online: 18 Oct 2017
AbstractforEnrichment of Ly6Chi monocytes by multiple GM-CSF injections with HBV vaccine contributes to viral clearance in a HBV mouse model | Full Text | References | PDF (1.5 MB) | Supplemental
  • 1450 Views
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Article
Epitope mapping of Ebola virus dominant and subdominant glycoprotein epitopes facilitates construction of an epitope-based DNA vaccine able to focus the antibody response in mice
Daniel A. J. Mitchell, Lesley C. Dupuy, Mariano Sanchez-Lockhart, Gustavo Palacios, Jaap W. Back, Katya Shimanovskaya, Sidhartha Chaudhury, Daniel R. Ripoll, Anders Wallqvist & Connie S. Schmaljohn
Pages: 2883-2893
Published online: 14 Nov 2017
AbstractforEpitope mapping of Ebola virus dominant and subdominant glycoprotein epitopes facilitates construction of an epitope-based DNA vaccine able to focus the antibody response in mice | Full Text | References | PDF (1.3 MB) | Supplemental
  • 1289 Views
  • 9 CrossRef citations
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Article
Intranasal immunization with a single dose of the fusion protein formulated with a combination adjuvant induces long-term protective immunity against respiratory syncytial virus
R. Garg, L. Latimer, V. Gerdts, A. Potter & S. van Drunen Littel-van den Hurk
Pages: 2894-2901
Published online: 18 Oct 2017
AbstractforIntranasal immunization with a single dose of the fusion protein formulated with a combination adjuvant induces long-term protective immunity against respiratory syncytial virus | Full Text | References | PDF (706.3 KB)
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Article
A DNA vaccine delivered by dermal electroporation fully protects cynomolgus macaques against Lassa fever
Kathleen A. Cashman, Eric R. Wilkinson, Carl I. Shaia, Paul R. Facemire, Todd M. Bell, Jeremy J. Bearss, Joshua D. Shamblin, Suzanne E. Wollen, Kate E. Broderick, Niranjan Y. Sardesai & Connie S. Schmaljohn
Pages: 2902-2911
Published online: 07 Nov 2017
AbstractforA DNA vaccine delivered by dermal electroporation fully protects cynomolgus macaques against Lassa fever | Full Text | References | PDF (1 MB)
  • 2178 Views
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Review

Review
Plant-made vaccines and reagents for the One Health initiative
Edward Peter Rybicki
Pages: 2912-2917
Published online: 18 Oct 2017
AbstractforPlant-made vaccines and reagents for the One Health initiative | Full Text | References | PDF (400.4 KB)
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Research Paper

Article
Vaccines for emerging infectious diseases: Lessons from MERS coronavirus and Zika virus
Joel N. Maslow
Pages: 2918-2930
Published online: 14 Nov 2017
AbstractforVaccines for emerging infectious diseases: Lessons from MERS coronavirus and Zika virus | Full Text | References | PDF (536.4 KB)
  • 5481 Views
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Review

Review
Cancer vaccines and immunotherapeutic approaches in hepatobiliary and pancreatic cancers
Inga Hochnadel, Uta Kossatz-Boehlert, Nils Jedicke, Henrike Lenzen, Michael P. Manns & Tetyana Yevsa
Pages: 2931-2952
Published online: 07 Nov 2017
AbstractforCancer vaccines and immunotherapeutic approaches in hepatobiliary and pancreatic cancers | Full Text | References | PDF (803.2 KB) | Supplemental
  • 2951 Views
  • 13 CrossRef citations
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Research Papers

Article
Combinatorial peptide-based epitope mapping from Ebola virus DNA vaccines and infections reveals residue-level determinants of antibody binding
Daniel R. Ripoll, Daniel A. J. Mitchell, Lesley C. Dupuy, Anders Wallqvist, Connie Schmaljohn & Sidhartha Chaudhury
Pages: 2953-2966
Published online: 14 Nov 2017
AbstractforCombinatorial peptide-based epitope mapping from Ebola virus DNA vaccines and infections reveals residue-level determinants of antibody binding | Full Text | References | PDF (1.4 MB) | Supplemental
  • 1073 Views
  • 4 CrossRef citations
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Article
Advax4 delta inulin combination adjuvant together with ECMX, a fusion construct of four protective mTB antigens, induces a potent Th1 immune response and protects mice against Mycobacterium tuberculosis infection
Bruno de Paula Oliveira Santos, Monalisa Martins Trentini, Renato Beilner Machado, Mara Rúbia Nunes Celes, André Kipnis, Nikolai Petrovsky & Ana Paula Junqueira-Kipnis
Pages: 2967-2976
Published online: 05 Dec 2017
AbstractforAdvax4 delta inulin combination adjuvant together with ECMX, a fusion construct of four protective mTB antigens, induces a potent Th1 immune response and protects mice against Mycobacterium tuberculosis infection | Full Text | References | PDF (1.1 MB)
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Commentary

Article Commentary
Q-vaxcelerate: A distributed development approach for a new Coxiella burnetii vaccine
Patrick M. Reeves, Susan Raju Paul, Ann E. Sluder, Timothy A. Brauns & Mark C. Poznansky
Pages: 2977-2981
Published online: 17 Nov 2017
AbstractforQ-vaxcelerate: A distributed development approach for a new Coxiella burnetii vaccine | Full Text | References | PDF (675.2 KB)
  • 1476 Views
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Research Papers

Article
Application of replication-defective West Nile virus vector to non-flavivirus vaccine targets
Maryann Giel-Moloney, Michael Vaine, Linong Zhang, Mark Parrington, Beata Gajewska, Thorsten U. Vogel, Svetlana O. Pougatcheva, Xiaochu Duan, Timothy Farrell, Irina Ustyugova, Sanjay Phogat, Harry Kleanthous & Konstantin V. Pugachev
Pages: 2982-2986
Published online: 18 Oct 2017
AbstractforApplication of replication-defective West Nile virus vector to non-flavivirus vaccine targets | Full Text | References | PDF (680.1 KB)
  • 1132 Views
  • 3 CrossRef citations
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Article
The dynamics of immunoglobulin V-gene usage and clonotype expansion in mice after prime and boost immunizations as analyzed by NGS
Diego J. Farfán-Arribas, Shuying Liu, Shixia Wang & Shan Lu
Pages: 2987-2995
Published online: 30 Oct 2017
AbstractforThe dynamics of immunoglobulin V-gene usage and clonotype expansion in mice after prime and boost immunizations as analyzed by NGS | Full Text | References | PDF (1.2 MB) | Supplemental
  • 1151 Views
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Article
Screening of primary gp120 immunogens to formulate the next generation polyvalent DNA prime-protein boost HIV-1 vaccines
Shixia Wang, Te-hui Chou, Anthony Hackett, Veronica Efros, Yan Wang, Dong Han, Aaron Wallace, Yuxin Chen, Guangnan Hu, Shuying Liu, Paul Clapham, James Arthos, David Montefiori & Shan Lu
Pages: 2996-3009
Published online: 07 Nov 2017
AbstractforScreening of primary gp120 immunogens to formulate the next generation polyvalent DNA prime-protein boost HIV-1 vaccines | Full Text | References | PDF (1.5 MB) | Supplemental
  • 1012 Views
  • 7 CrossRef citations
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Article
DNA vaccines elicit durable protective immunity against individual or simultaneous infections with Lassa and Ebola viruses in guinea pigs
Kathleen A. Cashman, Eric R. Wilkinson, Suzanne E. Wollen, Joshua D. Shamblin, Justine M. Zelko, Jeremy J. Bearss, Xiankun Zeng, Kate E. Broderick & Connie S. Schmaljohn
Pages: 3010-3019
Published online: 17 Nov 2017
AbstractforDNA vaccines elicit durable protective immunity against individual or simultaneous infections with Lassa and Ebola viruses in guinea pigs | Full Text | References | PDF (1.2 MB)
  • 1262 Views
  • 16 CrossRef citations
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Article
Chimpanzee adenoviral vectors as vaccines for outbreak pathogens
Katie Ewer, Sarah Sebastian, Alexandra J. Spencer, Sarah Gilbert, Adrian V. S. Hill & Teresa Lambe
Pages: 3020-3032
Published online: 14 Nov 2017
AbstractforChimpanzee adenoviral vectors as vaccines for outbreak pathogens | Full Text | References | PDF (611.1 KB)
  • 5454 Views
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