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Volume 5, Issue 4

mAbs

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mAbs, Volume 5, Issue 4 (2013)

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mAbs, Volume 5, Issue 4 (2013)

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Editorial

Antibodies to watch in 2013

Mid-year update

Janice M Reichert

Pages: 513-517

Published online: 09 May 2013

AbstractforAntibodies to watch in 2013 | Full Text | References | PDF (165.7 KB)

2117 Views
63 CrossRef citations
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Open Access

Short Communication

Brief Report

Targeting endogenous nuclear antigens by electrotransfer of monoclonal antibodies in living cells

Guillaume Freund, Annie-Paule Sibler, Dominique Desplancq, Mustapha Oulad-Abdelghani, Marc Vigneron, Julian Gannon, Marc H. Van Regenmortel & Etienne Weiss

Pages: 518-522

Published online: 29 May 2013

AbstractforTargeting endogenous nuclear antigens by electrotransfer of monoclonal antibodies in living cells | Full Text | References | PDF (802.8 KB) | Supplemental

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Open Access

Report

Article

Deep mutational scanning of an antibody against epidermal growth factor receptor using mammalian cell display and massively parallel pyrosequencing

Charles M. Forsyth, Veronica Juan, Yoshiko Akamatsu, Robert B. DuBridge, Minhtam Doan, Alexander V. Ivanov, Zhiyuan Ma, Dixie Polakoff, Jennifer Razo, Keith Wilson & David B. Powers

Pages: 523-532

Published online: 29 May 2013

AbstractforDeep mutational scanning of an antibody against epidermal growth factor receptor using mammalian cell display and massively parallel pyrosequencing | Full Text | References | PDF (4.4 MB) | Supplemental

3230 Views
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Open Access

Article

Highly efficient selection of epitope specific antibody through competitive yeast display library sorting

Vinita Puri, Emily Streaker, Ponraj Prabakaran, Zhongyu Zhu & Dimiter S. Dimitrov

Pages: 533-539

Published online: 29 May 2013

AbstractforHighly efficient selection of epitope specific antibody through competitive yeast display library sorting | Full Text | References | PDF (853.3 KB) | Supplemental

1537 Views
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Free Access

Article

Generation and characterization of a unique reagent that recognizes a panel of recombinant human monoclonal antibody therapeutics in the presence of endogenous human IgG

Xiangdan Wang, Valerie Quarmby, Carl Ng, Anan Chuntharapai, Theresa Shek, Charles Eigenbrot, Robert F. Kelley, Steven Shia, Krista M McCutcheon, John Lowe, Cecilia Leddy, Kyle Coachman, Gary Cain, Felix Chu, Isidro Hotzel, Mauricio Maia, Eric Wakshull & Jihong Yang

Pages: 540-554

Published online: 29 Apr 2013

AbstractforGeneration and characterization of a unique reagent that recognizes a panel of recombinant human monoclonal antibody therapeutics in the presence of endogenous human IgG | Full Text | References | PDF (2.2 MB) | Supplemental

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Free Access

Article

Characterization of a surrogate murine antibody to model anti-human CD3 therapies

Fabien Dépis, Eric Hatterer, Romain Ballet, Bruno Daubeuf, Laura Cons, Sophie Glatt, Walter Reith, Marie Kosco-Vilbois & Yann Dean

Pages: 555-564

Published online: 18 Apr 2013

AbstractforCharacterization of a surrogate murine antibody to model anti-human CD3 therapies | Full Text | References | PDF (1 MB)

1977 Views
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Free Access

Article

Comparability analysis of anti-CD20 commercial (rituximab) and RNAi-mediated fucosylated antibodies by two LC-MS approaches

Chen Li, Anthony Rossomando, Shiaw-Lin Wu & Barry L. Karger

Pages: 565-575

Published online: 25 Apr 2013

AbstractforComparability analysis of anti-CD20 commercial (rituximab) and RNAi-mediated fucosylated antibodies by two LC-MS approaches | Full Text | References | PDF (2.1 MB) | Supplemental

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Free Access

Article

Analytical FcRn affinity chromatography for functional characterization of monoclonal antibodies

Tilman Schlothauer, Petra Rueger, Jan Olaf Stracke, Hubert Hertenberger, Felix Fingas, Lothar Kling, Thomas Emrich, Georg Drabner, Stefan Seeber, Johannes Auer, Stefan Koch & Apollon Papadimitriou

Pages: 576-586

Published online: 29 May 2013

AbstractforAnalytical FcRn affinity chromatography for functional characterization of monoclonal antibodies | Full Text | References | PDF (404.6 KB)

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Article

The human natural killer cytotoxic cell line NK-92, once armed with a murine CD16 receptor, represents a convenient cellular tool for the screening of mouse mAbs according to their ADCC potential

Béatrice Clémenceau, Régine Vivien, Catherine Pellat, Michael Foss, Gilles Thibault & Henri Vié

Pages: 587-594

Published online: 29 May 2013

AbstractforThe human natural killer cytotoxic cell line NK-92, once armed with a murine CD16 receptor, represents a convenient cellular tool for the screening of mouse mAbs according to their ADCC potential | Full Text | References | PDF (768.7 KB)

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Free Access

Article

Expression of antibodies using single open reading frame (sORF) vector design

Demonstration of manufacturing feasibility

Wendy R. Gion, Rachel A. Davis-Taber, Dean A. Regier, Emma Fung, Limary Medina, Ling C. Santora, Sahana Bose, Alexander V. Ivanov, Barbara A. Perilli-Palmer, Chris M. Chumsae, Joseph G. Matuck, Yune Z. Kunes & Gerald R. Carson

Pages: 595-607

Published online: 31 May 2013

AbstractforExpression of antibodies using single open reading frame (sORF) vector design | Full Text | References | PDF (3.6 MB) | Supplemental

3341 Views
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Open Access

Article

Monoclonal antibody disulfide reduction during manufacturing

Untangling process effects from product effects

Katariina M. Hutterer, Robert W. Hong, Jonathon Lull, Xiaoyang Zhao, Tian Wang, Rex Pei, M. Eleanor Le, Oleg Borisov, Rob Piper, Yaoqing Diana Liu, Krista Petty, Izydor Apostol & Gregory C. Flynn

Pages: 608-613

Published online: 18 Apr 2013

AbstractforMonoclonal antibody disulfide reduction during manufacturing | Full Text | References | PDF (516.3 KB)

6633 Views
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Article

Influence of FCGRT gene polymorphisms on pharmacokinetics of therapeutic antibodies

Christophe Passot, Nicolas Azzopardi, Sylvaine Renault, Nadine Baroukh, Christophe Arnoult, Marc Ohresser, Michèle Boisdron-Celle, Erick Gamelin, Hervé Watier, Gilles Paintaud & Valérie Gouilleux-Gruart

Pages: 614-619

Published online: 25 Apr 2013

AbstractforInfluence of FCGRT gene polymorphisms on pharmacokinetics of therapeutic antibodies | Full Text | References | PDF (527.4 KB)

1625 Views
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