Unilateral Acute Retinal Necrosis with Contralateral Non-necrotizing Herpetic Uveitis

ABSTRACT

Purpose

The objective of this study is to report a case of unilateral acute retinal necrosis (ARN) with contralateral eye presenting as non-necrotizing herpetic uveitis.

Case reports

Case 1: A 48-year-old female presented at our clinic with blurred vision in the right eye for 7 days. She was diagnosed with ARN in the left eye 2 weeks ago. Ophthalmic examination revealed reduced visual acuity in the right eye (20/33) with the presence of optic disc swelling and macular exudation without peripheral necrotic lesions. With systemic antiviral therapy, optic disc swelling of the right eye vanished gradually, and the visual acuity improved to 20/20. Loss of retinal nerve fiber layer (RNFL) and decreased retinal thickness in the corresponding area occurred during follow-up.

Conclusion

Non-necrotizing herpetic uveitis may occur in the contralateral eye of unilateral ARN under rare conditions. Structure abnormities, including loss of RNFL and focal decreased retinal thickness, are irretrievable.

KEYWORDS:

• Acute retinal necrosis
• viral uveitis
• optic disc
• non-necrotizing uveitis
• vasculitis
• herpetic virus

Declaration of interest

The authors have no proprietary or commercial interest in any drugs and equipment used in this article.

Additional information

Funding

The authors thank the support provided by The Capital Health Research and Development of Special (No.SF-2018-2-1081) and Capital Medical University Affiliated Beijing Tongren Hospital Key Medical Development Plan (trzdyxzy201801). The funding organization had no role in the design or conduct of this research.