Synthesis of Neonicotinoid analogues and study their toxicological aspects on Spodoptera littoralis and Schizaphis graminum

Abstract

Various Neonicotinoid guanidine/amidine analogues 1–3 were synthesized by the reaction of cyanoguanidine with acetylpyrimidines or diacetylpyridine. Their spectral analyses identified the synthesized compounds 1–3. The preliminary bioassays showed that all synthesized compounds showed moderate insecticidal activities against cotton leafworm Spodoptera littoralis (Boisd.) and Wheat Aphid (Schizaphis graminum).

Keywords:

• Cyanoguanidine
• Neonicotinoid
• Spodoptera littoralis
• Aphids

Disclosure statement

No potential conflict of interest was reported by the authors.