ABSTRACT
Background
Platelet-rich plasma injection has become an effective treatment for partial rotator cuff tears. This study evaluates the efficacy of PRP versus steroids injection in pain relief for partial rotator cuff tears.
Study design
Prospective clinical trial.
Setting
Alexandria Main University Hospital.
Patients and methods
Sixty patients with symptomatic partial RCTs undergoing US-guided subacromial injection were randomly allocated into two equal groups: either steroids or PRP. Pain score, shoulder function, failure rate after injection, and complications were recorded.
Results
VAS score was significantly lower in the steroid group at week 2 follow-up than the PRP group (p 0.001). However, it was shorter, extended for 8 weeks in steroid in comparison to 4 months in PRP group. There was an insignificant difference among groups in the simple shoulder test at 2 and 4 weeks follow-up, and the test was significantly higher in PRP group at 6, 8, 12 weeks, and 4 month follow-up (P = 0.049, 0.001, 0.001, 0.001). Pain did not improve in six patients in steroid group and one patient in PRP group. Pain on injection was reported by six patients in the steroid group and 13 patients in PRP group (p = 0.052). Elevated blood sugar was significantly higher in the steroid group after the injection (p 0.001).
Conclusion
Subacromial PRP injection may have a prolonged analgesic effect and superior shoulder functional improvement than steroids in patients with partial RCTs.
Disclosure statement
No potential conflict of interest was reported by the author(s).
Ethical approval
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. This research involved only patient charts. An institutional permission was approved to the study prior to submission for publication.
Informed consent
Individual patient consent was taken prior to the procedure.
Authors’ contributions
Dorreya M. Fikry: the principal investigator and senior author, revising the whole manuscript.
Tarek M. Sarhan: senior author, revising the whole manuscript.
Mohamed M. El Sawy: methodology section, PRP preparation.
Moutaz E. Elabbasy: data analysis, writing revision and figure formatting.
Radwa S. Raslan: scientific writing and data analysis and reference styling.