Acknowledgments
We thank Dr. Nikola Cihoric for sharing the database of http://clinicaltrial.co/.
Declaration of interest
O. Elicin and M. Ozsahin have received consultation fees from Merck Group for attending advisory board meetings. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.