Managing overactive bladder

Abstract

Overactive bladder (OAB) is a common and distressing condition which is known to increase with age and has a significant effect on quality of life. Whilst OAB is a symptomatic diagnosis, many patients will require basic investigations prior to initiating the appropriate management.

This article will review the initial clinical assessment and management of women complaining of OAB including conservative measures and drug therapy, and will also focus on the role of estrogen. In addition, the management of refractory OAB will also be discussed including more invasive strategies such as neuromodulation, Botulinum Toxin, and reconstructive surgery.

摘要

膀胱过度活动症（OAB）是一种常见且令人痛苦的疾病, 其随着年龄增长发病率增加, 并对生活质量具有显著影响。虽然OAB是症状性诊断, 但许多患者在开始适当的治疗前需进行基本情况的调查。

本文将回顾主诉OAB女性的初步临床评估和管理, 包括保守治疗和药物治疗, 将重点关注雌激素的作用。此外, 还将讨论难治性OAB的管理, 包括更多的侵入性疗法, 如神经调节, 肉毒杆菌毒素和重建手术。

Keywords:

• Overactive bladder
• antimuscarinics
• estrogen
• β3 agonists
• Botulinum Toxin
• neuromodulation