Optimizing diagnostic and therapeutic measures for different types of melasma based on the biophysical characteristics of facial skin

ABSTRACT

The goal was to determine ways to optimize diagnostic and therapeutic measures for various types of melasma in the outpatient setting of the dermatovenerological ambulatory clinic. The study involved 112 women with a confirmed diagnosis of facial melasma whose disease lasted for at least 2 years. The severity of patient pigmentation was evaluated using the Melasma Area Severity Index and the Melasma Severity Scale. There was a significant increase in melanin levels across all melasma types, an increase in erythema in the dermal type, and an increase in sebum production in the epidermal type.

KEYWORDS:

• dermatology
• melasma
• hormonal status
• neoangiogenesis
• IPL therapy

Disclosure statement

No potential conflict of interest was reported by the authors.

Declaration of Conflicting Interests

The authors declared no potential conflicts of interest concerning the research, authorship, and/or publication of this article.

Data availability statement

Data is avaible at https://drive.google.com/drive/u/2/my-drive

Ethical approval

The study protocol was approved by the Ethics Committee of I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation. The study was conducted by the rules of the Declaration of Helsinki.

Informed consent

All subjects gave written informed consent before participation.

Additional information

Funding

The authors received no financial support for the research, authorship, and(or) publication of this article.