Abstract
Serial anthropometric measurements and metabolic monitoring determinations were obtained in 40 very low birth weight (VLBW) infants (< 1500 g at birth) who were consecutively studied after admission to the intensive care nursery. The first 13 infants received primarily supplemental peripheral parenteral nutrition (PN) (Group I). The next 27 infants received conventional care consisting of intravenous glucose plus oral alimentation as tolerated (Group II). Group I demonstrated somatic growth comparable to that of Group II over intervals ranging from 3-7 weeks, without developing any clinically significant metabolic disturbances or cholestasis. Group I had significantly increased skinfold thickness values compared to Group II. Supplemental peripheral PN offers a safe alternative to entcral feedings for the promotion of adequate somatic growth in the VLBW infant during the first several weeks of life.