Abstract
The need for improved antibacterials, particularly in light of increasing antibacterial resistance, dominated the 36th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) meeting in New Orleans, Louisiana. New and improved quinolones, led by levofloxacin (currently in review at the Food and Drug Administration; FDA), followed by grepafloxacin, trovafloxacin and sparfloxacin are all expected to facilitate major changes in therapy. New cephalosporins, macrolides and carbapenems will complement these new agents.