Abstract
In this day and age, it is rare to discover a medical breakthrough which defies decades of medical dogma. The concept of bacterial infection causing peptic ulcer represents such an event. After an explosion of scientific research during the 1980s, the ‘ulcer causing bacteria’ made it to popular news-stand magazines during the 1990s. Over this time span, Helicobacter pylori underwent two name changes, from Campylobacter pyloridis to Campylobacter pylori to its current moniker. This review covers our current understanding of the pathophysiology, diagnosis and treatment of Helicobacter pylori-associated gastroduodenal inflammatory states.