Meta-analysis and investigation of anti-infective therapies

Abstract

Meta-analysis offers an alternative approach to examining specific sub-groups, such as classes of antibiotics, types of bacteria as well as patient groups whose response to the agent under investigation may not be equivalent. In this review, the strengths and pitfalls of meta-analyses of anti-infective therapies will be discussed.

• meta-analysis
• once daily aminoglycoside therapy
• selective decontamination
• sepsis
• sub-group analysis