IBC’s 5th Annual Conference on Blood Substitutes

Abstract

IBC’s 5^th Annual Conference on Blood Substitutes was held on November 20-21, 1997. Approximately 100 medical researchers, academic scientists, blood substitute company speakers and representatives from major pharmaceutical companies with an interest or partner in the field attended. The papers presented focused on the progress in clinical trials for those compounds in human study, on preclinical models for predicting efficacy in humans, and on novel approaches and agents for the delivery of oxygen. Both perfluorocarbons (PFC) and haemoglobin-based oxygen carriers were described. Several lectures addressed the history of the field and future directions for laboratory and clinical investigation. The following is a summary of some of the presentations. This summary is divided into 3 sections. The first section provides a historical overview and discusses the changes in the perceived need for a blood substitute. Section 2 comprises an update of company activities. The final section focuses on likely future directions for laboratory and human clinical study.

• blood substitutes
• haemoglobin
• nitric oxide
• perfluorocarbons
• polyethylene glycol
• shock
• transfusions
• trauma