Abstract
Aims
This study was designed to investigate the association between COPD and activity of daily living among oldest-old in People's Republic of China.
Patients and methods
The data of Chinese Longitudinal and Health Longevity Study in 2014 was used, and those who were aged more than 80 years old were included. Both basic activity of daily living (BADL) and instrumental activity of daily living (IADL) were measured.
Results
A total of 4621 oldest-old (≥80 years old) were included. 32.1% (1482) of the oldest-old had BADL disability and 79.0% (3129) had IADL disability. The BADL disability and IADL disability rates were higher for participants with COPD than those without, and this difference was more robust among male (31.8% vs 25.6%, p=0.018). The IADL disability rate showed similar trends. Multivariate logistic regression analysis showed that the odds ratios of COPD on BADL disability and IADL disability were 1.261 (95% CI: 1.044–1.525) and 2.014 (95% CI: 1.561–2.598), respectively. The odds ratios of COPD on moderate to severe BADL disability and IADL disability were 1.007 (95% CI: 0.790–1.284) and 1.713 (95% CI: 1.397–2.100), respectively.
Conclusion
There were independent associations between COPD and disability among oldest-old in People's Republic of China, and the associations were greater among male population. Besides, COPD had a profound influence on the mild disability of BADL, while had a greater impact on the moderate and severe disability of IADL.
Supplementary material
Acknowledgments
This study is supported by research grants from Beijing Nova Program (Z181100006218085), Opening Foundation of State Key Laboratory of Kidney Diseases (KF-01-115), Opening Foundation (NCRCG-PLAGH-2017017), National Natural Science Foundation of China (81703285), Beijing Natural Science Foundation (7174350), Beijing Municipal Science and Technology Commission (Z161100005016021), Military Fund (15BJZ41, 17BJZ51). The views and opinions expressed in this paper are those of the authors and do not necessarily reflect the official position of the study sponsors.
Availability of data and materials
All data used in this study were available upon request.
Abbreviations
ADL, activity of daily living; BADL, basic activity of daily living; BMI, body mass index; CLHLS, Chinese Longitudinal Healthy Longevity Survey; DBP, diastolic blood pressure; IADL, instrumental activity of daily living.
Ethics approval
The study was approved by the Biomedical Ethics Committee of Peking University.
Author contributions
All authors contributed to data analysis, drafting and revising the article, gave final approval of the version to be published, and agree to be accountable for all aspects of the work.
Disclosure
The authors report no conflicts of interest in this work.