Abstract
Invasive fungal infections (IFIs) are among the most severe complications in recipients of hematopoietic stem cell transplantation (HSCT) recipients and in patients with hematological malignancies. An increasing number of uncommon fungal infections have been reported in this era of antifungal prophylaxis. Coprinopsis cinerea is a rare pathogen that causes opportunistic infections in the immunocompromised patients, including HSCT recipients and is associated with very high mortality rates. Herein, we present a successfully treated pediatric HSCT patient with breakthrough pulmonary IFI caused by Coprinopsis cinerea despite posaconazole, prophylaxis using multidisciplinary approaches.
Ethical Approval and Consent for Participate
Written consents in approval for publication of this manuscript were obtained from both the patients and parents. The publication of this case report has been approved by Shenzhen Children’s Hospital Ethics Committee (approval number 2021102).
Consent for Publication
Written consent was obtained from the parents of the patient for the participation of this study.
Acknowledgments
We thank the patient and parents for giving the consent for the publication of this paper.
Author Contributions
All authors made a significant contribution to the work reported, whether that is in the conception, study design, execution, acquisition of data, analysis and interpretation, or in all these areas; took part in drafting, revising or critically reviewing the article; gave final approval of the version to be published; have agreed on the journal to which the article has been submitted; and agree to be accountable for all aspects of the work.
Disclosure
The authors have no conflict of interests to declare for this work.