Sequential Therapy of Linezolid and Contezolid to Treat Vancomycin-Resistant Enterococcus faecium Pneumonia in a Centenarian Patient: Case Report

Abstract

Enterococcus faecium (E. faecium) is one of the core components of enterococci and causes serious illnesses in the elderly and immunocompromised patients. Due to its adaptive traits and antibiotic resistance, E. faecium has evolved as a worldwide hospital-associated pathogen, especially vancomsycin-resistant Enterococcus faecium (VREfm). Pneumonia caused by VREfm is quite rare in clinical settings, and optimal treatment has not yet been determined. Here, we present a case of nosocomial VREfm pneumonia with lung cavitation following adenovirus infection, which was successfully treated with linezolid and contezolid.

Keywords:

• vancomycin-resistant enterococcus
• Enterococcus faecium
• pneumonia
• contezolid

View correction statement:

Sequential Therapy of Linezolid and Contezolid to Treat Vancomycin-Resistant Enterococcus faecium Pneumonia in a Centenarian Patient: Case Report [Corrigendum]

Ethical Approval Statement

The studies involving human participants were reviewed and approved by The Second Medical Center, Chinese PLA general hospital. The patient’s spouse has provided written informed consent for the case details to be published.

Acknowledgments

The authors express their sincere gratitude to all the staff of the Department of Respiratory and Critical Care Medicine, The Second Medical Center of Chinese PLA General Hospital in Beijing, China.

Disclosure

The authors declare no conflict of interest. The research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.