Intracranial Myroides odoratimimus Infection After EVD Successfully Treated with Intravenous Plus Intraventricular Tigecycline: A Case Report

Abstract

Intracranial infections are the most serious and common postoperative complications with significant mortality and morbidity. Myroides odoratimimus (M. odoratimimus), a Gram-negative environmental species and an opportunistic microorganism, predominantly infects immunocompromised individuals. Limited clinical experiences and documented multidrug resistance have resulted in a scarcity of data on the treatment of M. odoratimimus infections. As far as we know, this is the first reported case of an intracranial M. odoratimimus infection with external ventricular drains (EVD) that was effectively treated with a combination of intravenous and intraventricular tigecycline in an immunocompetent adult host.

Keywords:

• Myroides odoratimimus
• M. odoratimimus
• intracranial infection
• immunocompetent host
• tigecycline

Ethics Approval and Patient Consent

Our study was approved by the Ethics Committee at Zhejiang Provincial People`s Hospital (approval number is 2022O386) in accordance with the ethical standards of Helsinki Declaration. The written and informed consent for publication of this case and any details was obtained from the patient`s husband as a legal guardian because the patient was unconscious, and the informed consent for publication of any details was also obtained if she regained consciousness in the further. We strictly abided by data protection legislation and ethical standards, patient`s personal information such as name, gender, hospitalization number won`t be appeared in terms of images, laboratory examination of our article.

Disclosure

The authors report no conflicts of interest in this work.

Additional information

Funding

This study was partially supported by the project “lncRNA-UCA1-microRNA-143-Notch1 regulates autophagy in myocardial ischemia reperfusion injury induced by cardiopulmonary bypass.” (No. 2020KY041).