Effect of Sleep Duration on Blood Pressure in Patients with SARS-CoV-2 Infection and Hypertensive Urgencies in Shanghai Fangcang Shelter Hospital

Abstract

Objective

To evaluate the effect of sleep duration on blood pressure in patients with hypertension urgencies combined with SARS-CoV-2 infection in a Fangcang shelter hospital.

Methods

From April 10, 2020 to May 20, 2022, we statistically analyzed the blood pressure and sleep conditions of 52 patients with combined hypertension urgencies and SARS-CoV-2 infection admitted in Shanghai National Convention and Exhibition Center Fangcang shelter hospital. They were divided into the short-term (daily sleep duration: <7 h) and normal sleep group (7–9 h). We performed a comparison of the control effects of basic antihypertensive drugs. Additionally, patients in the short-term sleep group underwent drug therapy for sleep regulation and continuous monitoring of blood pressure.

Results

Among these patients, the blood pressure was higher in the short-term sleep group than that of the normal sleep group, and also more difficult to control (p <0.05). Furthermore, the blood pressure of the patients in the short-term sleep group was more easily controlled after treatment with drugs for sleep regulation and basic antihypertensive drugs (p <0.05).

Conclusion

The blood pressure level in patients with combined SARS-CoV-2 infection and hypertension urgencies was higher in those with a shorter duration of daily sleep, and also more difficult to control in Fangcang shelter hospital. Drug therapy for sleep regulation should be administered early to obtain sufficient blood pressure control effects.

Keywords:

• hypertension urgencies
• shelter hospital
• sleep regulation
• Fangcang hospital
• blood pressure
• short-term sleep
• SARS-CoV-2
• COVID-19

Ethics Statement

The Ethics Review Committee of General Hospital of Central Theater Command of the Chinese People’s Liberation Army approved this study. The patients provided their verbal informed consent to participate from every patient we could contact by phone in this study. This is a medical assistance during a major emergency of infectious disease in China, and this paper is a public health management experience report, and the centers for disease control and prevention of General Hospital of Central Theater Command of the Chinese People’s Liberation Army does not allow paper materials with infectious diseases to be taken out of infected areas; thus, written informed consent for participation was not required for this study in accordance with the hospital legislation and the institutional requirements. This retrospective data study complies with the guidelines for human studies and is in accordance with the Declaration of Helsinki. We have withheld patient identification information in this paper and have not shared patient information with any third parties.

Acknowledgments

The authors are very grateful to the patient for his consent to the publication of this study. Jin-Hu Shi, Jian Ding and Hu Cheng should be considered as co-first authors.

Disclosure

The authors report no conflict of interest in this work.

Additional information

Funding

The authors do not declare a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.