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Inhalation Toxicology
International Forum for Respiratory Research
Volume 16, 2004 - Issue 1
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Research Article

Comparative Subchronic Inhalation Study of Smoke From the 1R4F and 2R4F Reference Cigarettes

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Pages 1-20 | Published online: 19 Oct 2008

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Sheppard A. Martin, Wendy M. Oshiro, Paul A. Evansky, Laura L. Degn, Allen D. Ledbetter, Jermaine Ford, Q. Todd Krantz, William R. LeFew, Tracey E. Beasley, Hisham El-Masri, Eva D. McLanahan, William K. Boyes & Philip J. Bushnell. (2014) Use of novel inhalation kinetic studies to refine physiologically-based pharmacokinetic models for ethanol in non-pregnant and pregnant rats. Inhalation Toxicology 26:10, pages 598-619.
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Christopher R. E. Coggins, Ann M. Jerome, Patrick D. Lilly, Willie J. McKinney$suffix/text()$suffix/text() & Michael J. Oldham. (2013) A comprehensive toxicological evaluation of three adhesives using experimental cigarettes. Inhalation Toxicology 25:sup2, pages 6-18.
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Hiroyuki Tsuji, K. Monica Lee, Kei. Yoshino, Hideaki Nakamura, George Lulham, Roger Renne & Hiroyuki Yoshimura. (2011) Comparison of the physiological and morphological effects of cigarette smoke exposure at comparable weekly doses on Sprague-Dawley rats. Inhalation Toxicology 23:1, pages 17-32.
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George J. Patskan, Kenneth F. Podraza, Kris Meurrens, Christopher R. E. Coggins, Bärbel Friedrichs, Birgit Gerstenberg, Willy Gomm, Peter Schnell, Regina Stabbert, Detlef Veltel, Susanne Weber & Piter Terpstra. (2008) Toxicological Comparisons of Three Styles of a Commercial U.S. Cigarette (Marlboro®) with the 1R4F Reference Cigarette. Inhalation Toxicology 20:7, pages 695-721.
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Charles L. Gaworski, Christopher R. E. Coggins & Edward L. Carmines. (2008) Palladium Alters Cigarette Smoke Toxicological Profile, but Accumulates in the Lungs of Rats During Inhalation Exposure. Inhalation Toxicology 20:2, pages 167-182.
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O. Moennikes, P. M. Vanscheeuwijck, B. Friedrichs, E. Anskeit & G. J. Patskan. (2008) Reduced Toxicological Activity of Cigarette Smoke by the Addition of Ammonia Magnesium Phosphate to the Paper of an Electrically Heated Cigarette: Subchronic Inhalation Toxicology. Inhalation Toxicology 20:7, pages 647-663.
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Kimberly C. Hodge-Bell, K. Monica Lee, Roger A. Renne, Kathy M. Gideon, Sam J. Harbo & Willie J. McKinney. (2007) Pulmonary Inflammation in Mice Exposed to Mainstream Cigarette Smoke. Inhalation Toxicology 19:4, pages 361-376.
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K. Monica Lee, Roger A. Renne, Sam J. Harbo, Mark L. Clark, Renee E. Johnson & Kathy M. Gideon. (2007) 3-Week Inhalation Exposure to Cigarette Smoke and/or Lipopolysaccharide in AKR/J Mice. Inhalation Toxicology 19:1, pages 23-35.
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Articles from other publishers (12)

Jef Serré, Ajime Tom Tanjeko, Carolien Mathyssen, An-Sofie Vanherwegen, Tobias Heigl, Rob Janssen, Eric Verbeken, Karen Maes, Bart Vanaudenaerde, Wim Janssens & Ghislaine Gayan-Ramirez. (2021) Enhanced lung inflammatory response in whole-body compared to nose-only cigarette smoke-exposed mice. Respiratory Research 22:1.
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Qian Sun, Hui Xu, Junchao Xue, Qianlei Yang, Chao Chen, Ping Yang, Aohan Han, Qingyun Tu, Jiachun Lu, Xiaohua Gao, Quanyong Xiang & Qizhan Liu. (2018) MALAT1 via microRNA‐17 regulation of insulin transcription is involved in the dysfunction of pancreatic β‐cells induced by cigarette smoke extract. Journal of Cellular Physiology 233:11, pages 8862-8873.
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Hiroki Daijo, Yuma Hoshino, Shinichi Kai, Kengo Suzuki, Kenichiro Nishi, Yoshiyuki Matsuo, Hiroshi Harada & Kiichi Hirota. (2016) Cigarette smoke reversibly activates hypoxia-inducible factor 1 in a reactive oxygen species-dependent manner. Scientific Reports 6:1.
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Seong Jin Choi, Sang Hyub Lee, Sang Jin Lee, Mi Jin Yang & Kyuhong Lee. (2016) Subchronic inhalation toxicity study of 3R4F reference cigarette smoke in rats. Molecular & Cellular Toxicology 12:3, pages 313-325.
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David Thorne, Joanne Kilford, Rebecca Payne, Linsey Haswell, Annette Dalrymple, Clive Meredith & Deborah Dillon. (2014) Development of a BALB/c 3T3 neutral red uptake cytotoxicity test using a mainstream cigarette smoke exposure system. BMC Research Notes 7:1.
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E Roemer, H Schramke, H Weiler, A Buettner, S Kausche, S Weber, A Berges, M Stueber, M Muench, E Trelles-Sticken, J Pype, K Kohlgrueber, H Voelkel & S Wittke. (2012) Mainstream Smoke Chemistry and in Vitro and In Vivo Toxicity of the Reference Cigarettes 3R4F and 2R4F . Beiträge zur Tabakforschung International/Contributions to Tobacco Research 25:1, pages 316-335.
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Michael J. Oldham, Hans-Juergen Haussmann, Willy Gomm, Lonnie T. Rimmer, Michael J. Morton & Willie J. McKinneyJr.Jr.. (2012) Discriminatory power of standard toxicity assays used to evaluate ingredients added to cigarettes. Regulatory Toxicology and Pharmacology 62:1, pages 49-61.
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E. Roemer, T.H. Ottmueller, H.-J. Urban & C. Baillet-Mignard. (2010) SKH-1 mouse skin painting: A short-term assay to evaluate the tumorigenic activity of cigarette smoke condensate. Toxicology Letters 192:2, pages 155-161.
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Ellen Jorgensen, Andy Stinson, Lin Shan, Jin Yang, Diana Gietl & Anthony P Albino. (2008) Cigarette smoke induces endoplasmic reticulum stress and the unfolded protein response in normal and malignant human lung cells. BMC Cancer 8:1.
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Atsuyasu SatoTomijiro HaraHajime NakamuraNoriko KatoYuma HoshinoNorihiko KondoMichiaki MishimaJunji Yodoi. (2006) Thioredoxin-1 Suppresses Systemic Inflammatory Responses Against Cigarette Smoking. Antioxidants & Redox Signaling 8:9-10, pages 1891-1896.
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E. Van Miert, X. Dumont & A. Bernard. (2005) CC16 as a marker of lung epithelial hyperpermeability in an acute model of rats exposed to mainstream cigarette smoke. Toxicology Letters 159:2, pages 115-123.
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. 2005. Medicinal Plants of the World, Volume 3. Medicinal Plants of the World, Volume 3 271 371 .

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