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COPD: Journal of Chronic Obstructive Pulmonary Disease Volume 6, 2009 - Issue 4
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ORIGINAL RESEARCH

Reduced Phosphorylation of the TGF-β Signal Transducer Smad2 in Emphysematous Human Lung

Outi Leppäranta Department of Medicine, Pulmonary Division, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland
,
Marjukka Myllärniemi Department of Medicine, Pulmonary Division, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland
,
Kaisa Salmenkivi HUSLAB, Department of Pathology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland
,
Vuokko L. Kinnula Department of Medicine, Pulmonary Division, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland
,
Jorma Keski-Oja HUSLAB, Department of Pathology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; Departments of Virology and Pathology, Haartman Institute, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland
&
Katri Koli Departments of Virology and Pathology, Haartman Institute, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland
Pages 234-241 | Published online: 11 Sep 2009

Citations (8)

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Read on this site (1)

Vuokko L Kinnula, Nobuhisa Ishikawa, Ulrich Bergmann & Steffen Ohlmeier. (2009) Proteomic approaches for studying human parenchymal lung diseases. Expert Review of Proteomics 6:6, pages 619-629.
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Articles from other publishers (7)

Shuang Bai & Li Zhao. (2021) Imbalance Between Injury and Defense in the COPD Emphysematous Phenotype. Frontiers in Medicine 8.
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Li Lin, Gang Hou, Dan Han, Yan Yin, Jian Kang & Qiuyue Wang. (2019) Ursolic acid alleviates airway-vessel remodeling and muscle consumption in cigarette smoke-induced emphysema rats. BMC Pulmonary Medicine 19:1.
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Antonino Di Stefano, Claudia Sangiorgi, Isabella Gnemmi, Paolo Casolari, Paola Brun, Fabio L.M. Ricciardolo, Marco Contoli, Alberto Papi, Pio Maniscalco, Paolo Ruggeri, Giuseppe Girbino, Francesco Cappello, Stelios Pavlides, Yike Guo, Kian Fan Chung, Peter J. Barnes, Ian M. Adcock, Bruno Balbi & Gaetano Caramori. (2018) TGF-β Signaling Pathways in Different Compartments of the Lower Airways of Patients With Stable COPD. Chest 153:4, pages 851-862.
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Fien M. Verhamme, Ken R. Bracke, Guy F. Joos & Guy G. Brusselle. (2015) Transforming Growth Factor-β Superfamily in Obstructive Lung Diseases. More Suspects Than TGF-β Alone. American Journal of Respiratory Cell and Molecular Biology 52:6, pages 653-662.
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Yong Zhang, Liang Shao, Aiqun Ma, Gongchang Guan, Junkui Wang, Yaping Wang & Gang Tian. (2013) Telmisartan delays myocardial fibrosis in rats with hypertensive left ventricular hypertrophy by TGF-β1/Smad signal pathway. Hypertension Research 37:1, pages 43-49.
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Joshua D Campbell, John E McDonough, Julie E Zeskind, Tillie L Hackett, Dmitri V Pechkovsky, Corry-Anke Brandsma, Masaru Suzuki, John V Gosselink, Gang Liu, Yuriy O Alekseyev, Ji Xiao, Xiaohui Zhang, Shizu Hayashi, Joel D Cooper, Wim Timens, Dirkje S Postma, Darryl A Knight, Lenburg E Marc, Hogg C James & Spira Avrum. (2012) A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK. Genome Medicine 4:8, pages 67.
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Frank Wempe, Silke De-Zolt, Katri Koli, Thorsten Bangsow, Nirmal Parajuli, Rio Dumitrascu, Anja Sterner-Kock, Norbert Weissmann, Jorma Keski-Oja & Harald von Melchner. (2010) Inactivation of sestrin 2 induces TGF-β signaling and partially rescues pulmonary emphysema in a mouse model of COPD. Disease Models & Mechanisms 3:3-4, pages 246-253.
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