Evaluation of an I177L gene-based five-gene-deleted African swine fever virus as a live attenuated vaccine in pigs

Yingnan Liua Shanghai Veterinary Research Institute, CAAS, Shanghai, People’s Republic of China;b Biosafety Research Center, CAAS, Shanghai, People’s Republic of ChinaView further author information

Zhenhua Xiea Shanghai Veterinary Research Institute, CAAS, Shanghai, People’s Republic of ChinaView further author information

Yao Lia Shanghai Veterinary Research Institute, CAAS, Shanghai, People’s Republic of ChinaView further author information

Yingying Songa Shanghai Veterinary Research Institute, CAAS, Shanghai, People’s Republic of ChinaView further author information

Dongdong Dic The Spirit Jinyu Biological Pharmaceutical Co. Ltd, Hohhot, People’s Republic of ChinaView further author information

Jingyi Liua Shanghai Veterinary Research Institute, CAAS, Shanghai, People’s Republic of China;b Biosafety Research Center, CAAS, Shanghai, People’s Republic of ChinaView further author information

Lang Gongd South China Agricultural University, Guangdong, People’s Republic of ChinaView further author information

Zongyan Chena Shanghai Veterinary Research Institute, CAAS, Shanghai, People’s Republic of China;b Biosafety Research Center, CAAS, Shanghai, People’s Republic of ChinaView further author information

Jinxian Wuc The Spirit Jinyu Biological Pharmaceutical Co. Ltd, Hohhot, People’s Republic of ChinaView further author information

Zhengqin Yec The Spirit Jinyu Biological Pharmaceutical Co. Ltd, Hohhot, People’s Republic of ChinaView further author information

Jianqi Liuc The Spirit Jinyu Biological Pharmaceutical Co. Ltd, Hohhot, People’s Republic of ChinaView further author information

Wanqi Yua Shanghai Veterinary Research Institute, CAAS, Shanghai, People’s Republic of ChinaView further author information

Lu Lva Shanghai Veterinary Research Institute, CAAS, Shanghai, People’s Republic of ChinaView further author information

Qiuping Zhonga Shanghai Veterinary Research Institute, CAAS, Shanghai, People’s Republic of ChinaView further author information

Chuanwen Tiana Shanghai Veterinary Research Institute, CAAS, Shanghai, People’s Republic of ChinaView further author information

Qingqing Songc The Spirit Jinyu Biological Pharmaceutical Co. Ltd, Hohhot, People’s Republic of ChinaView further author information

Heng Wangd South China Agricultural University, Guangdong, People’s Republic of ChinaCorrespondence[email protected]
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Hongjun Chena Shanghai Veterinary Research Institute, CAAS, Shanghai, People’s Republic of China;b Biosafety Research Center, CAAS, Shanghai, People’s Republic of ChinaCorrespondence[email protected]
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Kaichuang Shi, Kang Zhao, Haina Wei, Qingan Zhou, Yuwen Shi, Shenglan Mo, Feng Long, Liping Hu, Shuping Feng & Meilan Mo. (2023) Triplex Crystal Digital PCR for the Detection and Differentiation of the Wild-Type Strain and the MGF505-2R and I177L Gene-Deleted Strain of African Swine Fever Virus. Pathogens 12:9, pages 1092.
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Michelle D. Zajac, Jessie D. Trujillo, Jianxiu Yao, Rakshith Kumar, Neha Sangewar, Shehnaz Lokhandwala, Huldah Sang, Kylynn Mallen, Jayden McCall, Leeanna Burton, Deepak Kumar, Emily Heitmann, Tristan Burnum, Suryakant D. Waghela, Kelli Almes, Juergen Richt, Tae Kim & Waithaka Mwangi. (2023) Immunization of pigs with replication-incompetent adenovirus-vectored African swine fever virus multi-antigens induced humoral immune responses but no protection following contact challenge. Frontiers in Veterinary Science 10.
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Zhengwang Shi, Liyan Cao, Juncong Luo, Gaijing Zhou, Qingshan Zuo, XiangTao Liu, Yonghao Hu, Hong Tian & Haixue Zheng. (2023) A chemiluminescent magnetic microparticle immunoassay for the detection of antibody against African swine fever virus. Applied Microbiology and Biotechnology 107:11, pages 3779-3788.
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Guanglei Zhang, Wei Liu, Sicheng Yang, Shuai Song, Yunyun Ma, Guangqing Zhou, Xiaxia Liang, Chun Miao, Junhui Li, Yanhong Liu, Junjun Shao & Huiyun Chang. (2023) Evaluation of humoral and cellular immune responses induced by a cocktail of recombinant African swine fever virus antigens fused with OprI in domestic pigs. Virology Journal 20:1.
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Guoqiang Zhu, Jingjing Ren, Dan Li, Yi Ru, Xiaodong Qin, Tao Feng, Hong Tian, Bingzhou Lu, Dongfang Shi, Zhengwang Shi, Wenping Yang & Haixue Zheng. (2023) Combinational Deletions of MGF110-9L and MGF505-7R Genes from the African Swine Fever Virus Inhibit TBK1 Degradation by an Autophagy Activator PIK3C2B To Promote Type I Interferon Production . Journal of Virology.
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Naijun Han, Hailong Qu, Tiangang Xu, Yongxin Hu, Yongqiang Zhang & Shengqiang Ge. (2023) Summary of the Current Status of African Swine Fever Vaccine Development in China. Vaccines 11:4, pages 762.
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Evaluation of an I177L gene-based five-gene-deleted African swine fever virus as a live attenuated vaccine in pigs

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Evaluation of an I177L gene-based five-gene-deleted African swine fever virus as a live attenuated vaccine in pigs

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