Silencing Glypican-1 enhances the antitumor effects of Pictilisib via downregulating PI3K/Akt/ERK signaling in chemo-resistant esophageal adenocarcinoma

Akshay Pratapa Division of Gastrointestinal Tumor and Endocrine Surgery, University of Colorado, Aurora, CO, USACorrespondence[email protected]

Andrea Qualmana Division of Gastrointestinal Tumor and Endocrine Surgery, University of Colorado, Aurora, CO, USAView further author information

Hedlund Garrettb Department of Allergy and Clinical Immunology Flow Core, University of Colorado, Aurora, CO, USAView further author information

Lindsey Westbrookc Department of Pathology, University of Colorado, Aurora, CO, USAView further author information

Erlinda Thed Division of Cardiothoracic Surgery, University of Colorado, Aurora, CO, USAView further author information

Sanchayita Mitraa Division of Gastrointestinal Tumor and Endocrine Surgery, University of Colorado, Aurora, CO, USAView further author information

Mila Corderoe School of Science, Engineering, & Technology, St. Mary’s University, San Antonio, TX, USAView further author information

Kenneth Meza Mongea Division of Gastrointestinal Tumor and Endocrine Surgery, University of Colorado, Aurora, CO, USAView further author information

Juan- Pablo Idrovoa Division of Gastrointestinal Tumor and Endocrine Surgery, University of Colorado, Aurora, CO, USAView further author information

Argudit Chauhanf Department of Biomedical Engineering, University of Colorado, Boulder, USAView further author information

Linling Chengd Division of Cardiothoracic Surgery, University of Colorado, Aurora, CO, USAView further author information

Mitchell Jay Cohena Division of Gastrointestinal Tumor and Endocrine Surgery, University of Colorado, Aurora, CO, USAView further author information

Benedetto Mungog Division of Surgical Oncology, University of Colorado, Aurora, CO, USAView further author information

Sachin Wanih Division of Gastroenterology and Hepatology, University of Colorado, Aurora, CO, USAView further author information

Robert Alexander Meguidd Division of Cardiothoracic Surgery, University of Colorado, Aurora, CO, USAView further author information

Martin D McCarterg Division of Surgical Oncology, University of Colorado, Aurora, CO, USAView further author information

Xianzhong Mengd Division of Cardiothoracic Surgery, University of Colorado, Aurora, CO, USAView further author information

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