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Review

Advances in molecular therapies for targeting pathophysiology in spinal cord injury

, &
Pages 171-187 | Received 23 Jan 2023, Accepted 20 Mar 2023, Published online: 05 Apr 2023

Figures & data

Figure 1. The major recently reported neuroprotective strategies to target secondary injury mechanisms after spinal cord injury (SCI). Various secondary injury mechanisms contribute to continuous damage to the spinal cord after SCI. Numerous preclinical strategies have recently been reported to protect lesioned tissues and improved functional recovery.

Figure 1. The major recently reported neuroprotective strategies to target secondary injury mechanisms after spinal cord injury (SCI). Various secondary injury mechanisms contribute to continuous damage to the spinal cord after SCI. Numerous preclinical strategies have recently been reported to protect lesioned tissues and improved functional recovery.

Figure 2. Major recently reported molecular strategies for promoting axon regeneration and neuronal relays after central nervous system (CNS) injuries. Various molecular strategies have recently been reported to stimulate axon regeneration and neuronal relays after spinal cord injury (SCI) or other CNS lesions, including those that target either neuronal intrinsic factors or extrinsic factors around the lesioned spinal cord.

Figure 2. Major recently reported molecular strategies for promoting axon regeneration and neuronal relays after central nervous system (CNS) injuries. Various molecular strategies have recently been reported to stimulate axon regeneration and neuronal relays after spinal cord injury (SCI) or other CNS lesions, including those that target either neuronal intrinsic factors or extrinsic factors around the lesioned spinal cord.