In Silico Dosimetric Profiling of Human Nasal Inhaled Nanoparticles

Figures & data

FIGURE 1 Deposition fraction versus nanoparticle diameter. (Figure provided in color online.)

FIGURE 2 Deposition fraction (y-axis) versus airway number (x-axis). (Figure provided in color online.)

FIGURE 3 Regional deposition fraction diagram. (Figure provided in color online.)

TABLE 1 Site deposition diagram

Site	10 nm	20 nm	30 nm	40 nm	50 nm	60 nm	70 nm	80 nm	90 nm	100 nm
WL	0.475	0.51	0.478	0.434	0.39	0.353	0.32	0.294	0.272	0.255
LU	0.074	0.079	0.074	0.067	0.06	0.054	0.049	0.045	0.042	0.039
LL	0.146	0.155	0.145	0.131	0.118	0.107	0.097	0.089	0.082	0.077
RU	0.073	0.08	0.075	0.069	0.062	0.056	0.051	0.047	0.044	0.041
RM	0.036	0.04	0.038	0.035	0.032	0.029	0.026	0.024	0.022	0.021
RL	0.146	0.156	0.146	0.132	0.118	0.107	0.097	0.089	0.082	0.077
WL: whole lung; LU: left upper; LL: left lower; RU: right upper; RM: right middle; RL: right lower.

TABLE 2 Airway deposition diagram

Airway Number	10 nm	20 nm	30 nm	40 nm	50 nm	60 nm	70 nm	80 nm	90 nm	100 nm
1	0.003333	0.001939	0.001480	0.001268	0.001151	0.001078	0.001029	0.000994	0.000967	0.000947
2	0.005477	0.004704	0.004478	0.004393	0.004355	0.004336	0.004327	0.004321	0.004319	0.004317
3	0.004708	0.004089	0.003914	0.003852	0.003827	0.003818	0.003814	0.003813	0.003814	0.003815
4	0.003945	0.003124	0.002873	0.002772	0.002724	0.002698	0.002683	0.002674	0.002667	0.002663
5	0.005137	0.003569	0.003053	0.002821	0.002695	0.002617	0.002565	0.002528	0.002500	0.002478
6	0.007103	0.004441	0.003529	0.003101	0.002858	0.002702	0.002593	0.002513	0.002453	0.002405
7	0.009495	0.005649	0.004290	0.003638	0.003260	0.003013	0.002840	0.002711	0.002612	0.002533
8	0.014520	0.008417	0.006160	0.005052	0.004396	0.003962	0.003654	0.003423	0.003244	0.003102
9	0.019580	0.011420	0.008250	0.006657	0.005702	0.005064	0.004606	0.004262	0.003994	0.003781
10	0.023340	0.013780	0.009857	0.007840	0.006615	0.005787	0.005189	0.004738	0.004386	0.004104
11	0.029150	0.017890	0.012920	0.010290	0.008660	0.007544	0.006732	0.006115	0.005630	0.005241
12	0.034730	0.022270	0.016290	0.013000	0.010910	0.009462	0.008397	0.007581	0.006937	0.006417
13	0.040720	0.027560	0.020580	0.016550	0.013920	0.012070	0.010680	0.009608	0.008757	0.008067
14	0.045390	0.032780	0.025130	0.020460	0.017320	0.015040	0.013310	0.011960	0.010880	0.010000
15	0.049420	0.038650	0.030580	0.025320	0.021610	0.018840	0.016710	0.015030	0.013660	0.012540
16	0.052440	0.045650	0.037490	0.031690	0.027380	0.024050	0.021430	0.019310	0.017590	0.016150
17	0.051880	0.052710	0.045180	0.039090	0.034260	0.030370	0.027220	0.024620	0.022470	0.020670
18	0.048660	0.062460	0.056560	0.050270	0.044820	0.040210	0.036340	0.033090	0.030340	0.028010
19	0.033600	0.062120	0.061430	0.056550	0.051400	0.046710	0.042610	0.039070	0.036020	0.033390
20	0.018840	0.059590	0.067030	0.064620	0.060040	0.055310	0.050950	0.047080	0.043690	0.040720
21	0.005809	0.044920	0.061740	0.064130	0.061550	0.057660	0.053680	0.049990	0.046690	0.043770
22	0.000513	0.019030	0.035690	0.041490	0.041950	0.040360	0.038140	0.035850	0.033700	0.031760
23	0.000002	0.000837	0.002382	0.003215	0.003512	0.003547	0.003466	0.003337	0.003192	0.003045

TABLE 3 Regional deposition diagram

Region	10 nm	20 nm	30 nm	40 nm	50 nm	60 nm	70 nm	80 nm	90 nm	100 nm
Total	0.833	0.721	0.633	0.56	0.498	0.448	0.408	0.374	0.345	0.322
Head	0.343	0.2	0.146	0.117	0.099	0.086	0.077	0.07	0.064	0.059
TB	0.323	0.227	0.176	0.147	0.127	0.113	0.103	0.095	0.088	0.083
PL	0.167	0.294	0.311	0.296	0.272	0.249	0.228	0.209	0.193	0.18
TB: tracheobronchial; PL: pulmonary.