COVID-19 vaccination hesitancy and associated factors among solid organ transplant recipients in China

Figures & data

Figure 1. The flow chart for the third section of the questionnaire. COVID-19 = coronavirus disease 2019; SARS-CoV-2 = Severe acute respiratory syndrome coronavirus 2; Flu = influenza.

Table 1. Characteristics of the respondents for survey

	Variables	Total participants	Intent to Be Vaccinated		P-Value*
		(n,%)	Yes (n,%)	No or Uncertain (n,%)
	Total (n)	813	175	592
Sex	Male	551 (67.8)	128 (73.1)	392 (66.2)	.085
	Female	262 (32.2)	47 (26.9)	200 (33.8)
Age (years)	18~30	58 (7.1)	11 (6.3)	43 (7.3)	.077
	30~45	327 (40.2)	80 (45.7)	234 (39.5)
	45~60	358 (44.0)	65 (37.1)	269 (45.4)
	60+	70 (8.6)	19 (10.9)	46 (7.8)
Graft	Kidney	681 (83.8)	137 (78.3)	516 (87.2)	.011
	Liver	118 (14.5)	35 (20.0)	65 (11.0)
	Others	14 (1.7)	3 (1.7)	11 (1.9)
Post-transplantation time (years)	<0.25	21 (2.6)	6 (3.4)	14 (2.4)	.991
	0.25~2	160 (19.7)	38 (21.7)	118 (19.9)
	2~5	266 (32.7)	50 (28.6)	199 (33.6)
	5+	366 (45.0)	81 (46.3)	261 (44.1)
Residence	Rural	157 (19.3)	31 (17.7)	120 (20.3)	.455
	Urban	656 (80.7)	144 (82.3)	472(79.7)
Education level	High school or below	321 (39.5)	84 (48.0)	225 (38.0)	.018
	College and above	492 (60.5)	91 (52.0)	367 (62.0)
Marital status	Single	132 (16.2)	24 (13.7)	104 (17.6)	.408
	Married	628 (77.2)	138 (78.9)	453 (76.5)
	Divorced/Widowed	53 (6.5)	13 (7.4)	35 (5.9)
Occupation	Enterprise worker	209 (25.7)	47 (26.9)	150 (25.3)	.100
	Public institutions	131 (16.1)	18 (10.3)	103 (17.4)
	Self-employed	90 (11.1)	24 (13.7)	62 (10.5)
	Farmer	25 (3.1)	8 (4.6)	17 (2.9)
	Student	9 (1.1)	2 (1.1)	7 (1.2)
	Retired/vacation	163 (20.1)	32 (18.3)	121 (20.4)
	Other vocations	96 (11.8)	28 (16.0)	61 (10.3)
	Unemployed	90 (11.1)	16 (9.1	71 (12.0)
History of chronic disease	Cardiovascular disease^1	390 (48.0)	74 (42.3)	297 (50.2)	.067
	Metabolic disease	142 (17.5)	21 (12.0)	117 (19.8)	.019
	Cancer	10 (1.2)	2 (1.1)	8 (1.4)	1.000
	Allergic disease	12 (1.5)	2 (1.1)	10 (1.7)	1.000
	Others	107 (13.2)	31 (17.7)	69 (11.7)	.037
Have friend with medical background	Yes	307 (37.8)	60 (34.3)	227 (38.3)	.330
	No	506 (62.2)	115 (65.7)	365 (61.7)
Knew the guideline^2	Yes	477 (58.7)	105 (60.0)	337 (56.9)	.470
	No	336 (41.3)	70 (40.0)	225 (43.1)
Family members have vaccinated against COVID-19	Yes	622 (76.5)	139 (79.4)	439 (74.2)	.155
	No	191 (23.5)	36 (20.6)	153 (25.8)
Influenza vaccination during last season	Yes	49 (6.0)	10 (5.7)	29 (4.9)	.666
	No	764 (94.0)	165 (94.3)	563 (95.1)
The main source of information on COVID-19 vaccines	TV Programs and News Releases	307 (37.8)	69 (39.4)	222 (37.5)	.326
	Social Media Platforms	420 (51.7)	86 (49.1)	312 (52.7)
	Medical doctors, scientists and scientific journals	54 (6.6)	15 (8.6)	32 (5.4)
	Friends and relatives	32 (3.9)	5 (2.9)	26 (4.4)
Intention toward influenza vaccination for the current season	Yes	192 (23.6)	72 (41.1)	101 (17.1)	.000
	No	621 (76.4)	103 (58.9)	491 (82.9)
The vaccines are important for public health	Agree	686 (84.4)	161 (92.0)	481 (81.3)	.001
	Uncertain/Disagree	127 (15.6)	14 (8.0)	111 (18.8)
The vaccines are important for SOT patients	Agree	427 (52.5)	144 (82.3)	240 (40.5)	.000
	Uncertain/Disagree	386 (47.6)	31 (17.7)	352 (59.5)

¹Cardiovascular disease: Hypertension/Hyperlipidemia/Cardiovascular Heart Disease/Atrial Fibrillation. ²Guideline: The first edition of COVID-19 vaccine vaccination technical guideline

*P-values < .25 are presented in boldface.

Table 2. COVID-19 vaccine willingness rate stratified by attitude toward being vaccinated against influenza during the current season (2021–2022)

Attitude toward vaccination against SARS-CoV-2	Attitude toward being vaccinated against influenza during the current season (2021–2022)
	Influenza vaccine willingness (n = 173)	Influenza vaccine refuse (n = 594)
Yes	72	103
Uncertain	99	404
No	2	87

Figure 2. Reasons for hesitating to vaccinate against COVID-19 (multi-option). COVID-19 = coronavirus disease 2019; Unwilling means refuse to get COVID-19 vaccine; Unsure means not sure to get COVID-19 vaccine.

Figure 3. Multiple logistic regression analysis of factors associated with willingness to vaccinate against COVID-19. COVID-19 = coronavirus disease 2019; OR = odds ratio; CI = confidence interval; Flu = influenza.