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Emerging Microbes & Infections Volume 12, 2023 - Issue 1
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Letter

Transmission of recombinant enterovirus A76 (EV-A76) in Xinjiang Uighur autonomous region of China

Xiaolei Lia WHO WPRO Regional Polio Reference Laboratory, National Health Commission Key Laboratory for Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of ChinaView further author information
,
Huanhuan Lua WHO WPRO Regional Polio Reference Laboratory, National Health Commission Key Laboratory for Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of ChinaView further author information
,
Qiang Suna WHO WPRO Regional Polio Reference Laboratory, National Health Commission Key Laboratory for Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of ChinaView further author information
,
Peng Zhengb Jinan Institute for Food and Drug Control, Jinan, People’s Republic of ChinaView further author information
,
Bo Zhangc Teaching Department of Basic Medicine, Taishan Vocational College of Nursing, Tai’an, People’s Republic of ChinaView further author information
,
Hui Cuid Xinjiang Uygur Autonomous Region Center for Disease Control and Prevention, Urumqi, People’s Republic of ChinaView further author information
,
Haishu Tangd Xinjiang Uygur Autonomous Region Center for Disease Control and Prevention, Urumqi, People’s Republic of ChinaView further author information
,
Hehe Zhaoa WHO WPRO Regional Polio Reference Laboratory, National Health Commission Key Laboratory for Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of ChinaView further author information
,
Ying Liua WHO WPRO Regional Polio Reference Laboratory, National Health Commission Key Laboratory for Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of ChinaView further author information
,
Jie Jianga WHO WPRO Regional Polio Reference Laboratory, National Health Commission Key Laboratory for Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of ChinaView further author information
,
Jinbo Xiaoa WHO WPRO Regional Polio Reference Laboratory, National Health Commission Key Laboratory for Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of ChinaView further author information
&
Yong Zhanga WHO WPRO Regional Polio Reference Laboratory, National Health Commission Key Laboratory for Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of China;e Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, People’s Republic of ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-2692-5437View further author information
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Article: 2149350 | Received 09 Jun 2022, Accepted 15 Nov 2022, Published online: 20 Dec 2022

Figures & data

Figure 1. Phylogenetic analysis and recombination analysis of Xinjiang EV-A76 isolates. source: (a) The MCC phylogenetic tree and (b) the Bayesian Skyline Plot were constructed based on VP1 region of 41 sequences of EV-A76 strains worldwide. Phylogenetic tree based on the VP1 (c), P1 (d), P2 (e), and P3 (f) sequences of our EV-A76 isolate, the Shandong EV-A76 isolate, the Xinjiang EV-A89 isolate, and other EV-A prototype strains. (g) Gene structure organization, (h) similarity plot analyses of Xinjiang EV-A76 isolate, and (i) boot-scanning analysis of Xinjiang EV-A76 isolate.

Figure 1. Phylogenetic analysis and recombination analysis of Xinjiang EV-A76 isolates. source: (a) The MCC phylogenetic tree and (b) the Bayesian Skyline Plot were constructed based on VP1 region of 41 sequences of EV-A76 strains worldwide. Phylogenetic tree based on the VP1 (c), P1 (d), P2 (e), and P3 (f) sequences of our EV-A76 isolate, the Shandong EV-A76 isolate, the Xinjiang EV-A89 isolate, and other EV-A prototype strains. (g) Gene structure organization, (h) similarity plot analyses of Xinjiang EV-A76 isolate, and (i) boot-scanning analysis of Xinjiang EV-A76 isolate.
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