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Coronaviruses

Hybrid immunity and protection against infection during the Omicron wave in Malta

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Article: e2156814 | Received 11 Aug 2022, Accepted 05 Dec 2022, Published online: 02 Jan 2023

Figures & data

Figure 1. Flowchart showing inclusion criteria for cohort used in the study. *1 dose of Janssen vaccine is considered as a 2-dose regimen for this study (fully vaccinated).

Figure 1. Flowchart showing inclusion criteria for cohort used in the study. *1 dose of Janssen vaccine is considered as a 2-dose regimen for this study (fully vaccinated).

Table 1. Descriptive table for the cohort included in the study, showing denominators and column percentages.

Table 2. Univariate logistic regression, stratified by age groups.

Figure 2. Forest plot showing the Odds Ratios for Omicron infection with different vaccination groups described in Table 3, adjusted for age group. Red and blue indicate mRNA vaccines and Adenoviral vaccines respectively. NB: The “3 Adenoviral” regimen indicates 2 Adenoviral doses equivalent and 1 mRNA booster. Figure Footnote: The reference category is indicated by the vertical line in the graph, showing a 1.00 OR. This refers to the 2 mRNA vaccines, >20 weeks, no infection category (weakest immunity conferred).

Figure 2. Forest plot showing the Odds Ratios for Omicron infection with different vaccination groups described in Table 3, adjusted for age group. Red and blue indicate mRNA vaccines and Adenoviral vaccines respectively. NB: The “3 Adenoviral” regimen indicates 2 Adenoviral doses equivalent and 1 mRNA booster. Figure Footnote: The reference category is indicated by the vertical line in the graph, showing a 1.00 OR. This refers to the 2 mRNA vaccines, >20 weeks, no infection category (weakest immunity conferred).

Table 3. Multiple Logistic Regression for vaccination groups adjusted for age groups.

Figure 3. Forest plot comparing adenoviral to mRNA vaccine groups., adjusted for age group. NB: The “3 Adenoviral” regimen indicates 2 Adenoviral doses equivalent and 1 mRNA booster. Figure Footnote: The reference category is indicated by the vertical line in the graph, showing a 1.00 OR. This refers to the 2 mRNA vaccines, >20 weeks, no infection category (weakest immunity conferred).

Figure 3. Forest plot comparing adenoviral to mRNA vaccine groups., adjusted for age group. NB: The “3 Adenoviral” regimen indicates 2 Adenoviral doses equivalent and 1 mRNA booster. Figure Footnote: The reference category is indicated by the vertical line in the graph, showing a 1.00 OR. This refers to the 2 mRNA vaccines, >20 weeks, no infection category (weakest immunity conferred).
Supplemental material

Supplemental Material

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