3,438
Views
3
CrossRef citations to date
0
Altmetric
Research Article

Cervical HPV infection in Guangzhou, China: an epidemiological study of 198,111 women from 2015 to 2021

ORCID Icon, ORCID Icon, , , , , , ORCID Icon & ORCID Icon show all
Article: e2176009 | Received 02 Nov 2022, Accepted 23 Jan 2023, Published online: 15 Feb 2023

Figures & data

Figure 1. Age distribution according to diagnosis in Guangzhou, China. (A) Heatmap of age distribution according to diagnosis, standardized by the number of diagnosis groups. Blue square shows the percentage of positive diagnoses. (B) Age distribution (median, interquartile range) of cases according to the diagnosis. LSIL, low-grade squamous lesion; HSIL, high-grade squamous lesion; ICC, invasive cervical carcinoma; CA, condyloma acuminate, ASC-US/-H, atypical squamous cells of undetermined significance or HSIL not excluded.

Figure 1. Age distribution according to diagnosis in Guangzhou, China. (A) Heatmap of age distribution according to diagnosis, standardized by the number of diagnosis groups. Blue square shows the percentage of positive diagnoses. (B) Age distribution (median, interquartile range) of cases according to the diagnosis. LSIL, low-grade squamous lesion; HSIL, high-grade squamous lesion; ICC, invasive cervical carcinoma; CA, condyloma acuminate, ASC-US/-H, atypical squamous cells of undetermined significance or HSIL not excluded.

Table 1. Distribution of HPV types according to final diagnostic status among the 198111 females.

Table 2. Prevalence of HPV types in Guangzhou China by year.

Figure 2. High-risk HPV prevalence associated with the severity of intraepithelial lesions in Guangzhou, China. HPV, human papillomavirus; LSIL, low-grade squamous lesion; HSIL, high-grade squamous lesion; ICC, invasive cervical carcinoma.

Figure 2. High-risk HPV prevalence associated with the severity of intraepithelial lesions in Guangzhou, China. HPV, human papillomavirus; LSIL, low-grade squamous lesion; HSIL, high-grade squamous lesion; ICC, invasive cervical carcinoma.

Figure 3. Chord diagram of HPV type correlations in women with multiple infections in Guangzhou, China. HPV, human papillomavirus.

Figure 3. Chord diagram of HPV type correlations in women with multiple infections in Guangzhou, China. HPV, human papillomavirus.

Table 3. Single and multiple infection status in 42911 females with HPV infection.

Figure 4. Age-specific HPV prevalence among women in Guangzhou, China, according to diagnosis. HPV, human papillomavirus; LSIL, low-grade squamous lesion; HSIL, high-grade squamous lesion; ICC, invasive cervical carcinoma; CA, condyloma acuminate, ASC-US/-H, atypical squamous cells of undetermined significance or HSIL not excluded. Shaded areas represent 95% CIs.

Figure 4. Age-specific HPV prevalence among women in Guangzhou, China, according to diagnosis. HPV, human papillomavirus; LSIL, low-grade squamous lesion; HSIL, high-grade squamous lesion; ICC, invasive cervical carcinoma; CA, condyloma acuminate, ASC-US/-H, atypical squamous cells of undetermined significance or HSIL not excluded. Shaded areas represent 95% CIs.

Figure 5. Time to clearance of HPV infection in HPV-positive women during long-term monitoring. HPV, human papillomavirus. Shaded areas represent 95% CIs.

Figure 5. Time to clearance of HPV infection in HPV-positive women during long-term monitoring. HPV, human papillomavirus. Shaded areas represent 95% CIs.
Supplemental material

Supplementary_materials.doc

Download MS Word (283.5 KB)

Data availability

The data that support the findings of this study are available from the corresponding author upon reasonable request.