California condors and DDT: Examining the effects of endocrine disrupting chemicals in a critically endangered species

Figures & data

Table 1. Half maximal activation (EC₅₀) and percent activation relative to maximal activation by estradiol (% Max E₂) of California condor estrogen receptors (ESRs) 1 and 2 by DDT and its metabolites. Adapted from Felton et al., 2015.

Structure	Name	ESR1 EC50	ESR1 % Max E2	ESR2 EC50	ESR2 % Max E2
	p,p'-DDT	6.6 × 10^−6 M	82.3 ± 5.3	5.3 × 10^−6 M	74.6 ± 9.6
	o,p'-DDT	3.6 × 10^−6 M	72.9 ± 4.0	2.9 × 10^−6 M	98.1 ± 12.7
	p,p'-DDD	2.6 × 10^−5 M	16.1 ± 1.9	2.5 × 10^−5 M	39.7 ± 1.3
	o,p'-DDD	2.7 × 10^−6 M	68.2 ± 7.0	3.8 × 10^−6 M	60.0 ± 6.6
	p,p'-DDE	1.4 × 10^−5 M	16.1 ± 2.4	5.9 × 10^−6 M	28.1 ± 3.0
	o,p'-DDE	3.2 × 10^−6 M	47.0 ± 5.8	2.9 × 10^−6 M	55.8 ± 5.2