Application of nanotechnology in animal nutrition: Bibliographic review

Figures & data

Table 1. List of nano-minerals used in animal nutrition

No.	List of nano-minerals and associated attributes	Ref.
1	Manganese nanoparticles enhance chicken growth performance, antioxidant status, and bone attributes without affecting feed intake, weight gain, or efficiency. Mn is described for proper antioxidant and immune system function. Mn is also reported as cofactor of transferases, lyase, hydrolysis, and oxidoreductases, essential for mitochondrial antioxidant system, apoptosis, bone development, and cell structure	Patra and Lalhriatpuii (2020) Palomares (2022) Pasquini et al. (2022).
2	Calcium and phosphorus are crucial for bone growth in animals and poultry. Nano-minerals can improve feed conversion efficiency and body weight gain by 50%, but decrease calcium and phosphorus excretion. Nano-minerals provide low-dose antibiotic possibilities, increase growth, eliminate residues, reduce pollutants, and make pollutant-free animal products. Furthermore, plant-based diets contain substantial amounts of inaccessible P phytates (60–80% of total P), which are not utilized efficiently by chickens due to the absence of phytase enzymes.	Hassan et al. (2016), Samanta et al. (2019) Selle et al. (2009) Baharuddin et al. (2009)
3	Selenium is crucial for development, fertility, immune system, hormone metabolism, cell proliferation, and antioxidant defense. Nano-Se supplementation improves pH, ammonia, fatty acid levels, fertility, sperm quality, and egg production in layer chickens. Nano-Se at 0.3 mg/g dry food was reported to have greater physiological effects in layer chicks. Similarly, purine derivative nutrition utilization and urinary excretion were dramatically enhanced by nano-Se supplementation.	Ghaffarizadeh et al. (2022) Nabi et al. (2020) Shi et al. (2011)
4	Chromium is vital for insulin sensitivity and metabolism in animals. Nanocomposite in pigs reduces glucose, cholesterol, and fatty acid content, while increasing protein and lipoprotein production. Chromium propionate improves egg production and reduces heat exhaustion in poultry. Chromium has been suggested as it promotes insulin sensitivity in cells by activating insulin receptor kinase function. Egg quality, Cr persistence in the body, in the eggshell, and levels in the liver has all been observed to improve as a result of Cr-picolinate nanoparticle supplementation.	Bakshi and Panigrahi (2022) Anderson (2003) Hassan et al. (2020)
5	Copper is essential for metabolic activity, physiological functions, immunological responses, connective tissue development, and nerve function. Inorganic Cu sulphate and CuO nanoparticles improve growth performance, immunity, and reduce inflammatory responses in poultry. Cu nanoparticles included in basal meals decreased intake without influencing laying hen body weight, egg output, mass, or quality. Grill chicken with Cu supplementation lowered growth performance but decreased excretion. Through fast absorption, toxicity, and interaction, nano-Cu improves animal production performance.	Rossi et al. (2020) Patra and Lalhriatpuii (2020)
6	Silver nanoparticles in weaned pigs reduce coliform content, pathogen concentration, bacterial counts, growth, antibacterial capability, lymphatic organ weight, newborn weight loss, and liver lesions in grilled meats. A nanosilver feed additive substantially reduces the bacterial count in the digestive tract of poultry, lowering E. coli, Streptococcus, Salmonella, and mesophilic bacteria. Nano-silver supplementation of 20, 40, and 60 ppm feeds resulted in a dose-dependent reduction in the weight of the lymphatic organs.	Fondevila et al. (2009) Bhanja and Verma, (2021) Al-Sultan et al. (2022)
7	Nano-zinc supplementation enhances broiler bird immune status and bioavailability, inhibiting mycotoxic fungi growth and mycotoxins, reducing feed treatment hazards.	Hussan et al. (2022)
8	Iron is crucial for hemoglobin and oxygen transport, while Fe nanoparticles may improve chicken growth, haematology, and immunity. Research on their use is limited, but high doses can cause embryonic growth retardation and nerve damage. Fe nanoparticles and Fe-sulfate diets in quail breeders did not affect feed intake, egg mass production, quality, fertility, or chick growth.	Scott et al. (2018) Turgud and Narinç (2022)

Figure 1. Summary of some types of nano particles.

Patra, A., & Lalhriatpuii, M. (2020). Progress and prospect of essential mineral nanoparticles in poultry nutrition and feeding—A review. Biological Trace Element Research, 197(1), 233–253. https://doi.org/10.1007/s12011-019-01959-1

 PubMed Web of Science ®Google Scholar

Palomares, R. A. (2022). Trace minerals supplementation with Great Impact on Beef Cattle immunity and health. Animals, 12(20), 2839. https://doi.org/10.3390/ani12202839

 Web of Science ®Google Scholar

Pasquini, M., Grosjean, N., Hixson, K. K., Nicora, C. D., Yee, E. F., Lipton, M., Blaby, I. K., Haley, J. D., & Blaby-Haas, C. E. (2022). Zng1 is a GTP-dependent zinc transferase needed for activation of methionine aminopeptidase. Cell Reports, 39(7), 110834. https://doi.org/10.1016/j.celrep.2022.110834

 PubMed Web of Science ®Google Scholar

Hassan, M., Ding, W., Shi, Z., & Zhao, S. (2016). Methane enhancement through co-digestion of chicken manure and thermo-oxidative cleaved wheat straw with waste activated sludge: AC/N optimization case. Bioresource Technology, 211, 534–541. https://doi.org/10.1016/j.biortech.2016.03.148

 PubMed Web of Science ®Google Scholar

Samanta, G., Mishra, S., Behura, N., Sahoo, G., Behera, K., Swain, R., Sethy, K., Biswal, S., & Sahoo, N. (2019). Studies on utilization of calcium phosphate nano particles as source of phosphorus in broilers. Animal Nutrition and Feed Technology, 19(1), 77–88. https://doi.org/10.5958/0974-181X.2019.00008.8

 Web of Science ®Google Scholar

Selle, P. H., Cowieson, A. J., & Ravindran, V. (2009). Consequences of calcium interactions with phytate and phytase for poultry and pigs. Livestock Science, 124(1–3), 126–141. https://doi.org/10.1016/j.livsci.2009.01.006

 Web of Science ®Google Scholar

Baharuddin, A. S., Wakisaka, M., Shirai, Y., Abd-Aziz, S., Abdul, R., & Hassan, M. (2009). Co-composting of empty fruit bunches and partially treated palm oil mill effluents in pilot scale. International Journal of Agricultural Research, 4(2), 69–78. https://doi.org/10.3923/ijar.2009.69.78

 Google Scholar

Ghaffarizadeh, A., Sotoudeh, E., Mozanzadeh, M. T., Sanati, A. M., & Ghasemi, A. (2022). Supplementing dietary selenium nano-particles increased growth, antioxidant capacity and immune-related genes transcription in Pacific whiteleg shrimp (Penaeus vannamei) juveniles. Aquaculture Reports, 25, 101215. https://doi.org/10.1016/j.aqrep.2022.101215

 Web of Science ®Google Scholar

Nabi, F., Arain, M., Hassan, F., Umar, M., Rajput, N., Alagawany, M., Syed, S., Soomro, J., Somroo, F., & Liu, J. (2020). Nutraceutical role of selenium nanoparticles in poultry nutrition: a review. World’s Poultry Science Journal, 76, 459–471. https://doi.org/10.1080/00439339.2020.1789535

 Web of Science ®Google Scholar

Shi, L., Xun, W., Yue, W., Zhang, C., Ren, Y., Liu, Q., Wang, Q., & Shi, L. (2011). Effect of elemental nano-selenium on feed digestibility, rumen fermentation, and purine derivatives in sheep. Animal Feed Science and Technology, 163(2–4), 136–142. https://doi.org/10.1016/j.anifeedsci.2010.10.016

 Web of Science ®Google Scholar

Bakshi, A., & Panigrahi, A. K. (2022). Chromium contamination in soil and its bioremediation: An overview. Advances in Bioremediation and Phytoremediation for Sustainable Soil Management: Principles, Monitoring and Remediation, 229–248. https://doi.org/10.1007/978-3-030-89984-4_15

 Google Scholar

Anderson, R. A. (2003). Chromium and insulin resistance. Nutrition Research Reviews, 16(2), 267–275. https://doi.org/10.1079/NRR200366

 PubMed Web of Science ®Google Scholar

Hassan, S., Hassan, F.-U., & Rehman, M. S.-U. (2020). Nano-particles of trace minerals in poultry nutrition: Potential applications and future prospects. Biological Trace Element Research, 195(2), 591–612. https://doi.org/10.1007/s12011-019-01862-9

 PubMed Web of Science ®Google Scholar

Rossi, B., Toschi, A., Piva, A., & Grilli, E. (2020). Single components of botanicals and nature-identical compounds as a non-antibiotic strategy to ameliorate health status and improve performance in poultry and pigs. Nutrition Research Reviews, 33(2), 218–234. https://doi.org/10.1017/S0954422420000013

 PubMed Web of Science ®Google Scholar

Fondevila, M., Herrer, R., Casallas, M., Abecia, L., & Ducha, J. (2009). Silver nanoparticles as a potential antimicrobial additive for weaned pigs. Animal Feed Science and Technology, 150(3–4), 259–269. https://doi.org/10.1016/j.anifeedsci.2008.09.003

 Web of Science ®Google Scholar

Bhanja, S., & Verma, S. (2021). Prospects of nano minerals in poultry nutrition. Indian Journal of Poultry Science, 56(1), 1–8. https://doi.org/10.5958/0974-8180.2021.00006.4

 Google Scholar

Al-Sultan, S. I., Hereba, A. R. T., Hassanein, K. M., Abd-Allah, S. M., Mahmoud, U. T., & Abdel-Raheem, S. M. (2022). The impact of dietary inclusion of silver nanoparticles on growth performance, intestinal morphology, caecal microflora, carcass traits and blood parameters of broiler chickens. Italian Journal of Animal Science, 21(1), 967–978. https://doi.org/10.1080/1828051X.2022.2083528

 Web of Science ®Google Scholar

Hussan, F., Krishna, D., Preetam, V. C., Reddy, P., & Gurram, S. (2022). Dietary supplementation of nano zinc oxide on performance, carcass, serum and meat quality parameters of commercial broilers. Biological Trace Element Research, 200(1), 348–353. https://doi.org/10.1007/s12011-021-02635-z

 PubMed Web of Science ®Google Scholar

Scott, A., Vadalasetty, K., Łukasiewicz, M., Jaworski, S., Wierzbicki, M., Chwalibog, A., & Sawosz, E. (2018, February). Effect of different levels of copper nanoparticles and copper sulphate on performance, metabolism and blood biochemical profiles in broiler chicken. Journal of Animal Physiology and Animal Nutrition, 102(1), e364–e373. https://doi.org/10.1111/jpn.12754

 PubMed Web of Science ®Google Scholar

Turgud, F. K., & Narinç, D. (2022). Influences of dietary supplementation with Maca (Lepidium meyenii) on performance, parameters of growth curve and carcass characteristics in Japanese quail. Animals, 12(3), 318. https://doi.org/10.3390/ani12030318

 Web of Science ®Google Scholar