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Open Access Medical Statistics Volume 7, 2017 - Issue
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Original Research

Optimal look back period and summary method for Elixhauser comorbidity measures in a US population-based electronic health record database

Yannick Fortin1 McLaughlin Centre for Population Health Risk Assessment;2 School of Epidemiology, Public Health and Preventive Medicine, University of Ottawa, Ottawa, ON, CanadaCorrespondence[email protected]
,
James AG Crispo1 McLaughlin Centre for Population Health Risk Assessment;2 School of Epidemiology, Public Health and Preventive Medicine, University of Ottawa, Ottawa, ON, Canada;3 Fulbright Canada;4 Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
,
Deborah Cohen2 School of Epidemiology, Public Health and Preventive Medicine, University of Ottawa, Ottawa, ON, Canada;5 Canadian Population Health Initiative, Canadian Institute for Health Information, Ottawa;6 Institute for Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada
,
Douglas S McNair7 Cerner Corporation, Kansas City, MO, USA
,
Donald R Mattison1 McLaughlin Centre for Population Health Risk Assessment;8 Risk Sciences International, Ottawa, ON, Canada
&
Daniel Krewski1 McLaughlin Centre for Population Health Risk Assessment;2 School of Epidemiology, Public Health and Preventive Medicine, University of Ottawa, Ottawa, ON, Canada;8 Risk Sciences International, Ottawa, ON, Canada
Pages 1-13 | Published online: 31 Jan 2017

Figures & data

Table 1 Patient demographic and encounter characteristics, for the complete, derivation, and validation datasets

Table 2 Prevalence of comorbid conditions by look back period, N = 3,273,298

Table 3 Adjusted odds of inhospital mortality and relative points by health condition(s) and look back period, n = 1,637,572

Table 4 Adjusted odds of inhospital mortality at 1 year and relative points by health condition(s) and look back period, n = 1,637,572

Table 5 Predictive performance by mortality outcome, look back period, and comorbidity summary method, n = 1,635,726

Figure S1 Comparisons of ROC curves across comorbidity summary methods by mortality outcome and look back period.

Abbreviations: ROC, receiver operating characteristic; AUROC, area under the receiver operating characteristic.
Figure S1 Comparisons of ROC curves across comorbidity summary methods by mortality outcome and look back period.

Figure S2 Comparisons of ROC curves across look back periods by mortality outcome and comorbidity summary method.

Abbreviations: ROC, receiver operating characteristic; AUROC, area under the receiver operating characteristic.
Figure S2 Comparisons of ROC curves across look back periods by mortality outcome and comorbidity summary method.

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