Drug discovery toward successful cell transplantation therapy for Parkinson's disease using human pluripotent stem cells

Figures & data

Fig. 1 Cell transplantation strategy using human PSCs for PD patients. PSCs are cultured and then differentiated into DA progenitors. These progenitors are transplanted. In order to promote the efficacy of the grafted DA neurons, the brain microenvironment should be definitively adapted to promote the survival, maturation, neurite extension, and synaptic formation of the grafted cells.