Molecular interaction between thiamine hydrochloride-DMSO binary mixture: a TDR spectroscopic approach

ABSTRACT

The dielectric measurements of thiamine hydrochloride (vitamin B₁ hydrochloride) and dimethyl sulphoxide (DMSO) binary mixtures have been carried out in the frequency range of 10 MHz to 50 GHz at 25°C, 20°C and 15°C using the TDR technique. The dielectric parameters such as complex dielectric permittivity ɛ*(ω), static dielectric permittivity (ɛ_s), relaxation time (τ), and asymmetric distribution parameter (β) are obtained by using Cole-Davidson model. These parameters are used to compute thermodynamic properties, Kirkwood correlation factor (g^eff), and excess molar volume (V^E). The heteromolecular H-bonding existing in the binary mixture is explained.

KEYWORDS:

• Time-domain reflectometry
• complex dielectric spectra
• relaxation time
• thermodynamic parameters
• Kirkwood correlation factor

Acknowledgments

The financial support from the SERB, Department of Science and Technology, New Delhi, is gratefully acknowledged (project No. SR/FTP/PS-203/2012) and Project No. DST Project-SB/S2/LOP-032/2013). For the financial support, the author VSP thanks the Mahajyoti fellowship (award no. MAHAJYOTI/Nag./Fellowship/2021-22/1042 (370)), the author HNL thanks the NFST fellowship (award no. 202122-NFST-MAH-00132), and the author GTJ thanks the CSIR-UGC NET JRF Fellowship (award no. 201610114624).

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

The work was supported by the Department of science and technology, New Delhi [DST Project-SB/S2/LOP-032/2013]; Ministry of Tribal Affairs [202122-NFST-MAH-00132]; Mahatma Jyotiba Phule Research fellowship [MAHAJYOTI/Nag./Fellowship/2021-22/1042 (370)]; University Grants Commission [201610114624].