Solid-state deprotection of dithioacetals using 1-benzyl-4-aza-1-azoniabicyclo[2.2.2]octane periodate

Abstract

Various dithioacetals have been deprotected to the corresponding carbonyl compounds under solvent-free conditions using 1-benzyl-4-aza-1-azoniabicyclo[2.2.2]octane periodate in the presence of aluminium chloride.

Keywords:

• DABCO
• Periodate
• Deprotection
• Dithioacetals
• Solvent-free conditions
• AlCl3

Acknowledgements

We gratefully acknowledge the funding support received for this project from the Isfahan University of Technology (IUT), I.R. Iran (A. R. H.) and Grant GM 33138 (A. E. R.) from the National Institutes of Health, USA.