ABSTRACT
In the present study, magnesium nanoparticles (Mg NPs) were synthesized utilizing an aqueous extract of Berberis aristate rhizome and evaluated for antimicrobial and anti-inflammatory activity. Technofunctional properties of rhizome powder were evaluated and during thermal stability evaluation four stages of decomposition with a maximum delta Y value of 76.04 % was observed. Optimization of Mg NPs was carried out by employing eight different concentrations (C1-C8) and the C4 showed maximum absorbance at 330 nm confirming the NPs synthesis. The Mg NPs showed the particle size of 62 nm, zeta potential of −24.7 mV and hexagonal mprphology. Potential inhibition against S. aureus and E. coli (76.78 ± 0.05% and 74.62 ± 0.17%)and anti-inflammatory activity ranging from 42.43 ± 0.07–82.92 ± 0.04% was observed for Mg NPs. Therefore, green synthesis of Mg NPs is a promising approach for the development ofbiological active NPs to cure microbial infections.
Acknowledgement
Aurthors greatfully acknowledge support by Researchers Supporting Project Number (RSPD2023R940), King Saud University, Riyadh, Saudi Arabia.
Disclosure statement
No potential conflict of interest was reported by the author(s).
Author contributions
Conceptualization, S.P., A.B., and P.C.; data curation, S.P.,A.B., S.P., and R.K.; formal analysis, F.W., S.L., S.T. and A.B.; methodology, S.P., P.C., and N.M .; project administration, S.L., A.N., and P.C.; validation, F.W., A.N., and P.C.; resources, F.W., S.L., A.B., S.T., and R.K.; investigation, S.P., A.B., S.M.A. and R.K.; writing – original draft preparation, S.P., S.T., M.S, A.N, A.B; writing – review and editing, G.G. and A.N.; visualization, A.B., and P.C.; supervision, F.W., S.L., A.B. G.G. and P.C. All authors have read and agreed to the published version of the manuscript.
Data availability statement
The data is contained within the article.