Genomic characteristics of Salmonella Montevideo and Pomona: impact of isolation source on antibiotic resistance, virulence and metabolic capacity

ABSTRACT

Salmonella enterica is known for its disease-causing serotypes, including Montevideo and Pomona. These serotypes have been found in various environments, including river water, sediments, food, and animals. However, the global spread of these serotypes has increased, leading to many reported infections and outbreaks. The goal of this study was the genomic analysis of 48 strains of S. Montevideo and S. Pomona isolated from different sources, including clinical. Results showed that environmental strains carried more antibiotic resistance genes than the clinical strains, such as genes for resistance to aminoglycosides, chloramphenicol, and sulfonamides. Additionally, the type 4 secretion system, was only found in environmental strains. .Also many phosphotransferase transport systems were identified and the presence of genes for the alternative pathway Entner-Doudoroff. The origin of isolation may have a significant impact on the ability of Salmonella isolates to adapt and survive in different environments, leading to genomic flexibility and a selection advantage.

KEYWORDS:

• Salmonella
• in silico
• antimicrobial resistance
• virulence
• metabolism

Acknowledgements

The authors thank CONAHCYT for the scholarship provided to Lennin Isaac Garrido-Palazuelos in his Phd studies.

Disclosure statement

No potential conflict of interest was reported by the author(s).

CRediT author statement

Lennin Isaac Garrido-Palazuelos: Conceptualization, Formal analysis, Investigation, Data Curation, Software, Visualization, Writing – Original Draft Preparation. José Roberto Aguirre Sánchez: Data Curation, Software, Visualization, Writing – Review & Editing Jose Andrés Medrano-Félix: Conceptualization, Investigation, Supervision, Writing – Review & Editing. Berenice Gonzáles-Torres: Data Curation, Writing – Review & Editing, Software. Cristóbal Chaidez-Quiróz: Writing – Review & Editing. Osvaldo López-Cuevas: Writing – Review & Editing. Nohelia Castro-Del Campo: Writing – Review & Editing.

Data availability statement

The data that support the findings of this study are available on request from the corresponding author, JAMF. The data are not publicly available due to restrictions of the repository.

Supplementary material

Supplemental data for this article can be accessed online at https://doi.org/10.1080/09603123.2024.2336597.

Additional information

Funding

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.