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Research Article

Green Extraction, Phytochemical Profiling, and Biological Evaluation of Dysphania ambrosioides: An In Silico and In Vitro Medicinal Investigation

, , , , , , , & ORCID Icon show all
Pages 97-114 | Received 26 Jun 2023, Accepted 03 Oct 2023, Published online: 16 Oct 2023
 

ABSTRACT

Parasitic and microbial infections present substantial health risks, requiring effective treatments amidst growing antibiotic resistance. This study delves into Dysphania ambrosioides medicinal properties, utilizing hydro distillation and ultrasonic methods for extraction, followed by GC-MS analysis. Assessments revealed potent anti-diabetic effects in the methanol extract, significant antioxidant activity in the DCM extract and oil, and resistance against Escherichia coli. This research underscores the potential of local flora for novel treatments, particularly in underdeveloped regions. It emphasizes the value of plant screening in bioprospecting efforts, suggesting further investigations into specific bioactive compounds for pharmaceutical applications.

Acknowledgments

Financial assistance from the BfR (SFP 1322-807) is thankfully acknowledged.

Disclosure Statement

No potential conflict of interest was reported by the author(s).

Data Availability Statement

Data are available on request from the authors.

Supplementary Material

Supplemental data for this article can be accessed online at https://doi.org/10.1080/10496475.2023.2267467

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